Research Areas
In this section, by far, most Axon Ligands™ are categorized as research tools that find their application in cell signaling and oncology. Targeting a multitude of specific enzymes and receptors, they either stimulate or block particular cellular signaling pathways that are implicated in various kinds of cancer. Naturally, all products in this section can also be found by their specific biological targets as listed in the sections of enzymes, receptors, transcription factors, proteins and/or signaling pathways. Besides the comprehensive set of compounds that targe cell signaling and oncology, selections of Axon Ligands™ have also been made for other research area's such as cardiovascular diseases, angiogenisis, epigenetics, stem cell research, among many others.
| Axon ID | Name | Description | From price | |
|---|---|---|---|---|
| 2746 | AG-120 | IDH1 mutant enzyme inhibitor | €125.00 | |
| 2745 | AG-221 | IDH2 mutant enzyme inhibitor | €95.00 | |
| 2122 | AGI 5198 | Inhibitor of R132 mutant isocitrate dehydrogenase 1 (IDH1) | €60.00 | |
| 2274 | AGI 6780 | Potent and selective inhibitor of the tumor-associated mutant IDH2 (R140Q) | €90.00 | |
| 3863 | BAY-1436032 | Highly selective, potent and orally available inhibitor of mutant Isocitrate Dehydrogenase 1 (mIDH1) | Inquire | |
| 4024 | Vorasidenib | First-in-class, potent, orally active, brain-penetrant dual mIDH1/2 | €140.00 | |
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