Research Areas
In this section, by far, most Axon Ligands™ are categorized as research tools that find their application in cell signaling and oncology. Targeting a multitude of specific enzymes and receptors, they either stimulate or block particular cellular signaling pathways that are implicated in various kinds of cancer. Naturally, all products in this section can also be found by their specific biological targets as listed in the sections of enzymes, receptors, transcription factors, proteins and/or signaling pathways. Besides the comprehensive set of compounds that targe cell signaling and oncology, selections of Axon Ligands™ have also been made for other research area's such as cardiovascular diseases, angiogenisis, epigenetics, stem cell research, among many others.
| Axon ID | Name | Description | From price | |
|---|---|---|---|---|
| 1369 | Apilimod | Cytokine inhibitor; IL-12 and IL-23 inhibitor | €110.00 | |
| 2500 | Apilimod dimesylate | Cytokine inhibitor; IL-12 and IL-23 inhibitor | €110.00 | |
| 3428 | CSF1R inhibitor compound 22 | Potent, cellular active and orally bioavailable CSF1R inhibitor | €130.00 | |
| 2800 | Ensemble Compound 159 | Cytokine inhibitor; IL-17A inhibitor | Inquire | |
| 3917 | GLPG2534 | Potent, selective and orally active IRAK4 inhibitor | €150.00 | |
| 3217 | HS-243 | Highly potent and selective IRAK-1/4 inhibitor | €90.00 | |
| 4237 | IL-4-inhibitor-1 | First IL-4 inhibitor | Recently added | €110.00 |
| 4235 | IRAK1/4 inhibitor 1 | Potent IRAK-1/4 inhibitor | Recently added | €120.00 |
| 1501 | PD0220245 | IL-8 antagonist | €120.00 | |
| 3054 | PLX5622 | Potent, specific, orally bioavailable and brain-penetrant inhibitor of CSF1R | €80.00 | |
| 2999 | RCGD 423 | gp130 signalling modulator | €95.00 | |
| 2324 | SC 144 hydrochloride | The first-in-class small-molecule gp130 inhibitor | €130.00 | |
| 4084 | Sotuletinib | Potent, selective and brain-penetrant inhibitor of CSF1R | €120.00 | |
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