Research Areas

In this section, by  far, most Axon Ligands™ are categorized as research tools that find their application in cell signaling and oncology. Targeting a multitude of specific enzymes and receptors, they either stimulate or block particular cellular signaling pathways that are implicated in various kinds of cancer. Naturally, all products in this section can also be found by their specific biological targets as listed in the sections of enzymes, receptors, transcription factors, proteins and/or signaling pathways. Besides the comprehensive set of compounds that targe cell signaling and oncology, selections of Axon Ligands™ have also been made for other research area's such as cardiovascular diseases, angiogenisis, epigenetics, stem cell research, among many others.

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Axon ID Name Description From price
1989 (+)-JQ1

Potent and selective BET bromodomain inhibitor

3822 (+)-JQ1 carboxylic acid (+)-JQ1 derivative; PROTAC precursor  Recently added €110.00
3696 ABBV-075 Highly potent and orally bioavailable BET bromodomain (BRD) inhibitor €110.00
3039 ACY-241 Selective and orally available HDAC6 inhibitor €120.00
2269 AK 1 Potent inhibitor of SIRT with good selectivity for SIRT2 over SIRT1 and SIRT3 €90.00
2270 AK 7 Potent, brain-permeable and selective inhibitor of SIRT2 €90.00
1490 Anacardic acid A HAT inhibitor €60.00
2394 AR-42 HDAC inhibitor €125.00
5052 Axon Ligands™ Epigenetic compound library Axon Ligands™ Epigenetic compound library Inquire
3833 AZD5153 HNT salt Potent, selective, and orally available BET/BRD4 bromodomain inhibitor Inquire
2635 BAY-598 Selective inhibitor of SMYD2 €110.00
2735 BCI-121 Inhibitor of SMYD3 €90.00
3115 Belinostat HDAC inhibitor €70.00
3397 BG45 HDAC inhibitor (1, 2, 3 Selective) €80.00
3037 BI-894999 Potent, selective and orally active BET inhibitor €165.00
1692 BIX 01294 trihydrochloride HMTase inhibitor (G9a and G9a-like protein) €80.00
2306 Bizine Potent LSD1 inhibitor with selectivity over MAO-A/B, and LSD2 €120.00
3399 BML-210 HDAC inhibitor €80.00
3716 BMS-986158 BET bromodomain (BRD) inhibitor Inquire
2471 BRD 73954 Dual HDAC 6/8 inhibitor with excellent selectivity over the other HDACs €85.00
1781 C 646 HAT inhibitor (p300/CBP selective) €60.00
2803 Cambinol Inhibitor of SIRT1 and SIRT2 €95.00
2776 CD161 Potent, selective, and orally active BET bromodomain inhibitor €135.00
3764 CFT-8634 Selective orally bioavailable BRD9 degrader Inquire
2250 CHR 6494 trifluoroacetate Specific, first-in-class inhibitor of histone kinase Haspin €120.00
2014 CI 994 HDAC inhibitor that causes histone hyperacetylation in living cells €70.00
2812 CM-272 First-in-class potent, selective and reversible inhibitor of G9a/DNMT €130.00
2594 CPI 0610 Selective and metabolically stable inhibitor of BET bromodomains Inquire
2622 CPI 4203 Selective inhibitor of KDM5 demethylases (H3K4 specific) €85.00
2573 CPI 455 Selective inhibitor of KDM5 demethylases (H3K4 specific) €95.00

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