Research Areas
In this section, by far, most Axon Ligands™ are categorized as research tools that find their application in cell signaling and oncology. Targeting a multitude of specific enzymes and receptors, they either stimulate or block particular cellular signaling pathways that are implicated in various kinds of cancer. Naturally, all products in this section can also be found by their specific biological targets as listed in the sections of enzymes, receptors, transcription factors, proteins and/or signaling pathways. Besides the comprehensive set of compounds that targe cell signaling and oncology, selections of Axon Ligands™ have also been made for other research area's such as cardiovascular diseases, angiogenisis, epigenetics, stem cell research, among many others.
| Axon ID | Name | Description | From price | |
|---|---|---|---|---|
| 1989 | (+)-JQ1 |
Potent and selective BET bromodomain inhibitor |
€60.00 | |
| 3822 | (+)-JQ1 carboxylic acid | (+)-JQ1 derivative; PROTAC precursor | €110.00 | |
| 3873 | (-)-JQ-1 | Inactive enantiomer of (+)-JQ1 | €120.00 | |
| 3696 | ABBV-075 | Highly potent and orally bioavailable BET bromodomain (BRD) inhibitor | €110.00 | |
| 3956 | ABBV-744 | First-in-class highly BDII (Bromodomain II)-selective BET bromodomain inhibitor | Inquire | |
| 3039 | ACY-241 | Selective and orally available HDAC6 inhibitor | €120.00 | |
| 2269 | AK 1 | Potent inhibitor of SIRT with good selectivity for SIRT2 over SIRT1 and SIRT3 | €90.00 | |
| 2270 | AK 7 | Potent, brain-permeable and selective inhibitor of SIRT2 | €90.00 | |
| 1490 | Anacardic acid A | HAT inhibitor | €60.00 | |
| 2394 | AR-42 | HDAC inhibitor | €125.00 | |
| 3944 | ARV-825 | Potent and selective protein BRD4 degrader | Inquire | |
| 5052 | Axon Ligands™ Epigenetic compound library | Axon Ligands™ Epigenetic compound library | Inquire | |
| 3833 | AZD5153 HNT salt | Potent, selective, and orally available BET/BRD4 bromodomain inhibitor | Inquire | |
| 2635 | BAY-598 | Selective inhibitor of SMYD2 | €110.00 | |
| 2735 | BCI-121 | Inhibitor of SMYD3 | €90.00 | |
| 3115 | Belinostat | HDAC inhibitor | €70.00 | |
| 3397 | BG45 | HDAC inhibitor (1, 2, 3 Selective) | €80.00 | |
| 3037 | BI-894999 | Potent, selective and orally active BET inhibitor | €165.00 | |
| 1692 | BIX 01294 trihydrochloride | HMTase inhibitor (G9a and G9a-like protein) | €80.00 | |
| 2306 | Bizine | Potent LSD1 inhibitor with selectivity over MAO-A/B, and LSD2 | €120.00 | |
| 3399 | BML-210 | HDAC inhibitor | €80.00 | |
| 3716 | BMS-986158 | BET bromodomain (BRD) inhibitor | Inquire | |
| 2471 | BRD 73954 | Dual HDAC 6/8 inhibitor with excellent selectivity over the other HDACs | €85.00 | |
| 1781 | C 646 | HAT inhibitor (p300/CBP selective) | €60.00 | |
| 2803 | Cambinol | Inhibitor of SIRT1 and SIRT2 | €95.00 | |
| 2776 | CD161 | Potent, selective, and orally active BET bromodomain inhibitor | €135.00 | |
| 3764 | CFT-8634 | Selective orally bioavailable BRD9 degrader | Inquire | |
| 2250 | CHR 6494 trifluoroacetate | Specific, first-in-class inhibitor of histone kinase Haspin | €120.00 | |
| 2014 | CI 994 | HDAC inhibitor that causes histone hyperacetylation in living cells | €70.00 | |
| 2812 | CM-272 | First-in-class potent, selective and reversible inhibitor of G9a/DNMT | €130.00 | |