Research Areas
In this section, by far, most Axon Ligands™ are categorized as research tools that find their application in cell signaling and oncology. Targeting a multitude of specific enzymes and receptors, they either stimulate or block particular cellular signaling pathways that are implicated in various kinds of cancer. Naturally, all products in this section can also be found by their specific biological targets as listed in the sections of enzymes, receptors, transcription factors, proteins and/or signaling pathways. Besides the comprehensive set of compounds that targe cell signaling and oncology, selections of Axon Ligands™ have also been made for other research area's such as cardiovascular diseases, angiogenisis, epigenetics, stem cell research, among many others.
| Axon ID | Name | Description | From price | |
|---|---|---|---|---|
| 3946 | Altiratinib | Balanced inhibitor for MET, TIE2 (TEK), and VEGFR2 (KDR) kinases | Inquire | |
| 1916 | AMG 208 | Inhibitor of c-MET receptor tyrosine kinase (RTK) | €95.00 | |
| 3945 | AMG-337 | Potent and exquisitely selective inhibitor of wild-type and some mutant forms of c-Met | Inquire | |
| 1838 | ARQ 197 | c-MET tyrosine kinase Inhibitor | €90.00 | |
| 4040 | BMS-777607 | potent, selective and orally bioavailable c-Met inhibitor | Inquire | |
| 3423 | Capmatinib | Highly potent, selective, ATP competitive and orally bioavailable c-MET inhibitor | €80.00 | |
| 1660 | Crizotinib | c-MET Inhibitor; NPM-ALK inhibitor | €70.00 | |
| 1582 | Foretinib | c-MET and VEGFR2 tyrosine kinase inhibitor | €90.00 | |
| 2553 | LY 2801653 | Orally bioavailable multi-kinase inhibitor with potent activity against c-MET | €120.00 | |
| 3975 | MGCD265 dihydrochloride | Orally active, potent MET/SMO dual inhibitor | €130.00 | |
| 1583 | PF 04217903 mesylate | c-MET tyrosine kinase Inhibitor | €80.00 | |
| 1914 | SGX 523 | ATP-competitive inhibitor of c-MET | €120.00 | |
| 1581 | SU 11274 | ATP-competitive inhibitor of c-MET | €90.00 | |
| 3864 | Volitinib dihydrochloride | ATP-competitive small molecule c-Met kinase inhibitor | Inquire | |
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