Research Areas

In ths section, by  far, most Axon Ligands™ are categorized as research tools that find their application in cell signaling and oncology. Targeting a multitude of specific enzymes and receptors, they either stimulate or block particular cellular signaling pathways that are implicated in various kinds of cancer. Naturally, all products in this section can also be found by their specific biological targets as listed in the sections of enzymes, receptors, transcription factors, proteins and/or signaling pathways. Besides the comprehensive set of compounds that targe cell signaling and oncology, selections of Axon Ligands™ have also been made for other research area's such as cardiovascular diseases, angiogenisis, epigenetics, stem cell research, among many others.

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Axon ID Name Description From price
1887 PFI-1 BET bromodomain (BRD) inhibitor €75.00
1853 PCI 34051 HDAC8 Inhibitor €90.00
2530 OTX 015 Potent inhibitor of BRD2, BRD3, and BRD4 with clear anti-proliferative activity €125.00
2843 OSS-128167 Selective SIRT6 inhibitor €125.00
2077 OG-L002 hydrochloride Inhibitor of lysine specific demethylase 1 (LSD1 aka KDM1A) €125.00
2442 OF-1 Potent bromodomain inhibitor (BRPF1 and BRPF2 selective) €80.00
2359 Nexturastat A HDAC6 inhibitor with good selectivity over HDAC1 and HDAC8 €95.00
1803 MS 275 Inhibitor of HDAC (1 and 3 Selective) €80.00
2505 Mocetinostat Class I selective HDAC inhibitor with broad spectrum antitumor activity €80.00
2081 ML 324 dihydrochloride Inhibitor of JMJD2 histone demethylase €125.00
1785 MG 149 HAT inhibitor (Tip60 and MOZ specific) €105.00
1707 MC 1568 HDAC inhibitor (class IIA selective) €85.00
2430 LW 479 HDAC inhibitor with cytotoxicity in a panel of breast cancer cell lines. €135.00
1548 LBH 589 HDAC1 Inhibitor €95.00
2319 L 002 Inhibitor of p300 HAT (KAT3B) and p53 acetylation €80.00

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