Research Areas
In ths section, by far, most Axon Ligands™ are categorized as research tools that find their application in cell signaling and oncology. Targeting a multitude of specific enzymes and receptors, they either stimulate or block particular cellular signaling pathways that are implicated in various kinds of cancer. Naturally, all products in this section can also be found by their specific biological targets as listed in the sections of enzymes, receptors, transcription factors, proteins and/or signaling pathways. Besides the comprehensive set of compounds that targe cell signaling and oncology, selections of Axon Ligands™ have also been made for other research area's such as cardiovascular diseases, angiogenisis, epigenetics, stem cell research, among many others.
| Axon ID | Name | Description | From price | |
|---|---|---|---|---|
| 3040 | Abivertinib | Potent oral, irreversible, third-generation EGFR TKI with selectivity for mutant EGFRs | €95.00 | |
| 1986 | AST 1306 tosylate | ErbB2 and EGFR inhibitor | €105.00 | |
| 2563 | AZD 3759 | Potent, orally active, brain-penetrant, EGFR tyrosine kinase inhibitor | €85.00 | |
| 2342 | AZD 9291 | Potent oral, irreversible, third-generation EGFR TKI with selectivity for mutant EGFRs | €95.00 | |
| 1433 | CI 1033 | EGFR tyrosine kinase inhibitor | €60.00 | |
| 2680 | EAI045 | Allosteric EGFR inhibitor (L858R/T790M-specific) | €105.00 | |
| 1760 | EGFR Inhibitor [879127-07-8] | Highly selective EGFR tyrosine kinase inhibitor | €125.00 | |
| 3192 | EMI48 | Inhibitor of EGFR triple mutants | €125.00 | |
| 1128 | Erlotinib hydrochloride | EGFR tyrosine kinase inhibitor | €70.00 | |
| 1393 | Gefitinib | EGFR tyrosine kinase inhibitor | €70.00 | |
| 2955 | NSC 228155 | EGFR tyrosine kinase activator; Inhibitor of KIX-KID interaction | €75.00 | |
| 1632 | OSI 420 | EGFR tyrosine kinase inhibitor | €90.00 | |
| 1665 | Pelitinib | EGFR tyrosine kinase inhibitor | €95.00 | |
| 2053 | TAK 165 | ErbB2/HER2 kinase inhibitor | €60.00 | |
| 1506 | WZ 4002 | EGFR kinase inhibitor (T790M specific) | €70.00 | |