Research Areas
In ths section, by far, most Axon Ligands™ are categorized as research tools that find their application in cell signaling and oncology. Targeting a multitude of specific enzymes and receptors, they either stimulate or block particular cellular signaling pathways that are implicated in various kinds of cancer. Naturally, all products in this section can also be found by their specific biological targets as listed in the sections of enzymes, receptors, transcription factors, proteins and/or signaling pathways. Besides the comprehensive set of compounds that targe cell signaling and oncology, selections of Axon Ligands™ have also been made for other research area's such as cardiovascular diseases, angiogenisis, epigenetics, stem cell research, among many others.
| Axon ID | Name | Description | From price | |
|---|---|---|---|---|
| 1744 | A 77-01 | TGF-βR 1 inhibitor; ALK 5 inhibitor | €80.00 | |
| 1421 | A 83-01 | TGF-βR 1 inhibitor; ALK 5 inhibitor | €70.00 | |
| 1708 | Dorsomorphin | Inhibitor of BMP signaling. Inhibits ALK2, 3 and 6 | €65.00 | |
| 2150 | Dorsomorphin dihydrochloride | Inhibitor of BMP signaling. Inhibits ALK2, 3 and 6 | €65.00 | |
| 1832 | GW 788388 | TGF-βR 1 inhibitor | €50.00 | |
| 2236 | IN 1130 | TGF-βR 1 inhibitor | €105.00 | |
| 2323 | ITD 1 | Selective inhibitor of TGFβ/Smad signaling that promotes cardiogenesis | €105.00 | |
| 2467 | ITD-1, (+)- | Selective inhibitor of TGFβ/Smad signaling that promotes cardiogenesis | €165.00 | |
| 2189 | K 02288 | Inhibitor of BMP signaling. Inhibits ALK1, 2, and 6 | €90.00 | |
| 1509 | LDN 193189 hydrochloride | Highly potent small molecule inhibitor of BMP type I receptors ALK2, ALK3, and ALK6 | €65.00 | |
| 2201 | LDN 212854 trihydrochloride | Potent ALK2-biased BMP type I receptor kinase inhibitor | €105.00 | |
| 1491 | LY 2157299 | TGF-βR2 inhibitor | €65.00 | |
| 1661 | SB 431542 | TGF-βR1 inhibitor; ALK inhibitor | €70.00 | |
| 2197 | SB 505124 | Selective inhibitor of TGF-β type I receptors ALK4 and ALK5 | €95.00 | |
| 2285 | SB 525334 | Potent and selective inhibitor of the TGF-βR1 (ALK5) receptor | €105.00 | |