Research Areas

In ths section, by  far, most Axon Ligands™ are categorized as research tools that find their application in cell signaling and oncology. Targeting a multitude of specific enzymes and receptors, they either stimulate or block particular cellular signaling pathways that are implicated in various kinds of cancer. Naturally, all products in this section can also be found by their specific biological targets as listed in the sections of enzymes, receptors, transcription factors, proteins and/or signaling pathways. Besides the comprehensive set of compounds that targe cell signaling and oncology, selections of Axon Ligands™ have also been made for other research area's such as cardiovascular diseases, angiogenisis, epigenetics, stem cell research, among many others.

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Axon ID Name Description From price
2821 PFM01 Inhibitor of MRE11 endonuclease €65.00
1379 PF 477736 CHK1 inhibitor €70.00
2651 OAC2 Oct4 and Nanog activating compound that enhances reprogramming efficiency €60.00
2599 NVP-TNKS656 Selective and orally active TNKS inhibitor and antagonist of Wnt pathway activity €95.00
2907 Nucleozin Influenza A nucleoprotein targeting molecule €95.00
1463 NU 7441 DNA-PK inhibitor €55.00
1370 NU 1025 PARP inhibitor €80.00
2564 NSC 59984 Activator of p53 that restores WT p53 signaling via p73 activation €95.00
1402 NSC 348884 NPM inhibitor €120.00
2016 NSC 319726 Reactivator of the p53 mutant p53R175 €95.00
2928 Niraparib Potent, selective, and orally available PARP1/2 inhibitor €105.00
2517 Napabucasin Oral first-in-class cancer stemness inhibitor that works by targeting STAT3 €105.00
2783 Motolimod Highly potent and selective TLR8 agonist €145.00
2671 ML385 Inhibitor of NRF2 €120.00
2641 ML334 Activator of NRF2 by inhibition of Keap1-NRF2 interactions €120.00

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