Research Areas
In ths section, by far, most Axon Ligands™ are categorized as research tools that find their application in cell signaling and oncology. Targeting a multitude of specific enzymes and receptors, they either stimulate or block particular cellular signaling pathways that are implicated in various kinds of cancer. Naturally, all products in this section can also be found by their specific biological targets as listed in the sections of enzymes, receptors, transcription factors, proteins and/or signaling pathways. Besides the comprehensive set of compounds that targe cell signaling and oncology, selections of Axon Ligands™ have also been made for other research area's such as cardiovascular diseases, angiogenisis, epigenetics, stem cell research, among many others.
| Axon ID | Name | Description | From price | |
|---|---|---|---|---|
| 1254 | Zebularine | DNA methyltransferase inhibitor | €95.00 | |
| 2469 | YK 4-279 | Inhibitor of ETV1, ERG and interactions of EWS-FLI1 and RNA helicase A | €95.00 | |
| 2268 | XL 413 hydrochloride | Potent, selective and orally bioavailable CDC7 inhibitor | €120.00 | |
| 1527 | XAV 939 | Tankyrase (TNKS) inhibitor | €80.00 | |
| 2369 | UPF 1069 | PARP-2 inhibitor with >26 fold selectivity over PARP1 | €75.00 | |
| 2100 | Trovafloxacin mesylate | Inhibitor of bacterial DNA gyrase and Topo IV | €95.00 | |
| 3302 | Tenofovir alafenamide | Prodrug of Tenofovir; HIV-1 reverse transcriptase inhibitor | Recently added | €70.00 |
| 3157 | Tenofovir | Selective inhibitor of HIV-1 reverse transcriptase | €60.00 | |
| 2914 | TAS-103 dihydrochloride | Dual inhibitor of topoisomerase I (Topo 1) and topoisomerase II (Topo 2) | €95.00 | |
| 2502 | Talazoparib | Potent, selective, and orally available PARP1/2 inhibitor | €90.00 | |
| 1670 | STF 083010 | IRE1α inhibitor | €95.00 | |
| 2314 | Stattic | Nonpeptidic small-molecule inhibitor of STAT3 activation, dimerization, and nuclear translocation | €50.00 | |
| 2731 | STAT5 Inhibitor 1 [285986-31-4] | Nonpeptidic small-molecule inhibitor of STAT5 activation | €90.00 | |
| 2200 | SRPIN 340 | Selective ATP-competitive inhibitor of SRPK kinase activity | €95.00 | |
| 2714 | SPHINX31 | Potent and selective inhibitor of SRPK1 kinase activity | €125.00 | |