Research Areas

In ths section, by  far, most Axon Ligands™ are categorized as research tools that find their application in cell signaling and oncology. Targeting a multitude of specific enzymes and receptors, they either stimulate or block particular cellular signaling pathways that are implicated in various kinds of cancer. Naturally, all products in this section can also be found by their specific biological targets as listed in the sections of enzymes, receptors, transcription factors, proteins and/or signaling pathways. Besides the comprehensive set of compounds that targe cell signaling and oncology, selections of Axon Ligands™ have also been made for other research area's such as cardiovascular diseases, angiogenisis, epigenetics, stem cell research, among many others.

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Axon ID Name Description From price
1254 Zebularine DNA methyltransferase inhibitor €95.00
2469 YK 4-279 Inhibitor of ETV1, ERG and interactions of EWS-FLI1 and RNA helicase A €95.00
2268 XL 413 hydrochloride Potent, selective and orally bioavailable CDC7 inhibitor €120.00
1527 XAV 939 Tankyrase (TNKS) inhibitor €80.00
2369 UPF 1069 PARP-2 inhibitor with >26 fold selectivity over PARP1 €75.00
2100 Trovafloxacin mesylate Inhibitor of bacterial DNA gyrase and Topo IV €95.00
2914 TAS-103 dihydrochloride Dual inhibitor of topoisomerase I (Topo 1) and topoisomerase II (Topo 2) €95.00
2502 Talazoparib Potent, selective, and orally available PARP1/2 inhibitor €105.00
1670 STF 083010 IRE1α inhibitor €95.00
2314 Stattic Nonpeptidic small-molecule inhibitor of STAT3 activation, dimerization, and nuclear translocation €50.00
2731 STAT5 Inhibitor 1 [285986-31-4] Nonpeptidic small-molecule inhibitor of STAT5 activation €90.00
2200 SRPIN 340 Selective ATP-competitive inhibitor of SRPK kinase activity €95.00
2714 SPHINX31 Potent and selective inhibitor of SRPK1 kinase activity €125.00
2606 Solithromycin Fluoroketolide antibiotic €135.00
2764 SIS3 Potent and selective inhibitor of Smad3 and TGF-βR1 signaling €135.00

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