Research Areas
In ths section, by far, most Axon Ligands™ are categorized as research tools that find their application in cell signaling and oncology. Targeting a multitude of specific enzymes and receptors, they either stimulate or block particular cellular signaling pathways that are implicated in various kinds of cancer. Naturally, all products in this section can also be found by their specific biological targets as listed in the sections of enzymes, receptors, transcription factors, proteins and/or signaling pathways. Besides the comprehensive set of compounds that targe cell signaling and oncology, selections of Axon Ligands™ have also been made for other research area's such as cardiovascular diseases, angiogenisis, epigenetics, stem cell research, among many others.
| Axon ID | Name | Description | From price | |
|---|---|---|---|---|
| 1216 | Zardaverine | PDE3 and PDE4 inhibitor | €75.00 | |
| 1225 | U 73122 | PLC inhibitor | €95.00 | |
| 1592 | SB 207499 | PDE4 inhibitor | €80.00 | |
| 1432 | Rolipram, (S)-(+)- | PDE4 inhibitor | €115.00 | |
| 1229 | Rolipram, (R)-(-)- | PDE4 inhibitor | €110.00 | |
| 1212 | Rolipram | PDE4 inhibitor | €65.00 | |
| 2352 | Roflumilast | First specific PDE4 inhibitor licensed for treatment of COPD | €90.00 | |
| 3179 | Pentoxifylline | Non-specific inhibitor of cAMP phosphodiesterases | €40.00 | |
| 1482 | Parogrelil | PDE3 inhibitor | €120.00 | |
| 1168 | Olprinone hydrochloride | PDE3 inhibitor | €119.00 | |
| 1127 | L 454560 | PDE4 inhibitor | Inquire | |
| 2730 | HJC0350 | Highly potent and selective EPAC2 antagonist | €95.00 | |
| 3326 | HJC0197 | Potent EPAC antagonist | Recently added | €90.00 |
| 2847 | ESI-08 | Selective EPAC antagonist | €145.00 | |
| 3169 | Crisaborole | Potent PDE4 inhibitor; Anti-inflammatory agent | €60.00 | |