Research Areas
In ths section, by far, most Axon Ligands™ are categorized as research tools that find their application in cell signaling and oncology. Targeting a multitude of specific enzymes and receptors, they either stimulate or block particular cellular signaling pathways that are implicated in various kinds of cancer. Naturally, all products in this section can also be found by their specific biological targets as listed in the sections of enzymes, receptors, transcription factors, proteins and/or signaling pathways. Besides the comprehensive set of compounds that targe cell signaling and oncology, selections of Axon Ligands™ have also been made for other research area's such as cardiovascular diseases, angiogenisis, epigenetics, stem cell research, among many others.
| Axon ID | Name | Description | From price | |
|---|---|---|---|---|
| 3025 | Z944 | Highly selective, orally available Ca2+ channel blocker (T-type voltage gated) | €125.00 | |
| 1221 | SKF 96365 hydrochloride | Ca2+ channel blocker | €105.00 | |
| 1823 | Pregabalin | Reduces synaptic signaling by binding to α2δ subunits | €85.00 | |
| 1274 | PNU 37883 hydrochloride | K+ channel blocker (ATP sensitive, vascular) | €85.00 | |
| 3158 | Otilonium bromide | Ca2+ channel blocker | €70.00 | |
| 2068 | Nifedipine | Ca2+ channel blocker (L-type voltage gated) | €55.00 | |
| 3254 | Nicardipine | Ca2+ channel antagonist | Recently added | €50.00 |
| 3185 | L651582 | Ca2+ channel blocker | €120.00 | |
| 1448 | Felodipine | Ca2+ channel blocker | €65.00 | |
| 2952 | Fantofarone | Highly potent and specific Ca2+ channel antagonist | €125.00 | |
| 1868 | CRAC inhibitor 44 | Potent and selective CRAC ion channel blocker | €110.00 | |
| 2458 | Clemizole | Inhibitor of the transient receptor potential channel TRPC5 | €75.00 | |
| 1252 | CGS 9343B | Calmodulin inhibitor | €110.00 | |
| 1732 | CaSR antagonist 18c | Calcium-sensing receptor (CaSR) antagonist | €125.00 | |
| 1818 | Calhex 231 hydrochloride | NAM of the extracellular CaSR | €99.00 | |