Research Areas

In ths section, by  far, most Axon Ligands™ are categorized as research tools that find their application in cell signaling and oncology. Targeting a multitude of specific enzymes and receptors, they either stimulate or block particular cellular signaling pathways that are implicated in various kinds of cancer. Naturally, all products in this section can also be found by their specific biological targets as listed in the sections of enzymes, receptors, transcription factors, proteins and/or signaling pathways. Besides the comprehensive set of compounds that targe cell signaling and oncology, selections of Axon Ligands™ have also been made for other research area's such as cardiovascular diseases, angiogenisis, epigenetics, stem cell research, among many others.

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Axon ID Name Description From price
1683 Y 27632 dihydrochloride ROCK1 and ROCK2 inhibitor €65.00
2381 WH-4-023 Orally active src-family selective lck inhibitor €90.00
1562 TWS 119 GSK-3β inhibitor €70.00
1854 TTP 22 Inhibitor of Casein kinase 2 (CK2) €105.00
2560 Tilfrinib Brk inhibitor with antiproliferative activity in breast tumor cells €95.00
1535 Thiazovivin ROCK inhibitor and iPSC stimulator; Stem cell related €90.00
2010 TDZD 8 Selective and non-ATP-competitive inhibitor of GSK-3β €90.00
5006 Stem Cell CSD inhibitor Set Set of CHIR 99021, SU5402, and DAPT, inhibitors of GSK-3, FGFR, and γ-secretase, resp. €155.00
2130 Stem Cell Alternative 2i inhibitor Set Set of SRC inhibitor CGP77675 (Axon 2097) and GSK-3 inhibitor CHIR99021 (Axon 1386) €110.00
5007 Stem Cell 5i inhibitor Set Set of five inhibitors for neural differentiation of human pluripotent stem cells. €220.00
5009 Stem Cell 4i inhibitor Set Set of Thiazovivin, SB 431542, PD 0325901, and CHIR 99021 (inhibitors of ROCK, TGF-β, MEK, and GSK-3 resp.) €190.00
2547 SR 3029 A potent, highly specific CK1δ/CK1ε inhibitor €135.00
1635 Sotrastaurin PKC inhibitor €75.00
1923 SMI 4a ATP-competitive and selective inhibitor of Pim kinases €75.00
1407 SKI 606 Bcr-Abl and Src tyrosine kinase inhibitor €75.00

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