Research Areas
In ths section, by far, most Axon Ligands™ are categorized as research tools that find their application in cell signaling and oncology. Targeting a multitude of specific enzymes and receptors, they either stimulate or block particular cellular signaling pathways that are implicated in various kinds of cancer. Naturally, all products in this section can also be found by their specific biological targets as listed in the sections of enzymes, receptors, transcription factors, proteins and/or signaling pathways. Besides the comprehensive set of compounds that targe cell signaling and oncology, selections of Axon Ligands™ have also been made for other research area's such as cardiovascular diseases, angiogenisis, epigenetics, stem cell research, among many others.
| Axon ID | Name | Description | From price | |
|---|---|---|---|---|
| 1291 | AEG 3482 | JNK inhibitor | €85.00 | |
| 2002 | AS 602801 | JNK inhibitor, which inhibited JNK1, JNK2 and JNK3 | €70.00 | |
| 2179 | ASK1 Inhibitor 10 | Potent, selective, and orally bioavailable ASK1 inhibitor | €125.00 | |
| 1516 | AZD 6244 | MEK1 and MEK2 inhibitor | €60.00 | |
| 1999 | AZD 8330 | MEK 1 inhibitor | €105.00 | |
| 1358 | BIRB 796 | MAPK inhibitor (p38 specific) | €65.00 | |
| 3346 | BIX02188 | Potent MEK5 inhibitor | €110.00 | |
| 1808 | BIX02188-Me | MEK5 inhibitor; ERK5 inhibitor | €110.00 | |
| 1809 | BIX02189 | MEK5 inhibitor; ERK5 inhibitor | €110.00 | |
| 2856 | BMS 582949 | Inhibitor of p38α MAPK | €155.00 | |
| 2025 | CC-401 | ATP-competitive JNK inhibitor | €115.00 | |
| 2634 | CC-930 | Potent, selective, and orally active anti-fibrotic JNK inhibitor | €95.00 | |
| 1694 | FR 180204 | ERK inhibitor; AP-1 inhibitor | €95.00 | |
| 1761 | GSK 1120212 | MEK1 and MEK2 inhibitor | €70.00 | |
| 3059 | GW 284543 hydrochloride | Selective MEK5 inhibitor | €95.00 | |