Research Areas
In ths section, by far, most Axon Ligands™ are categorized as research tools that find their application in cell signaling and oncology. Targeting a multitude of specific enzymes and receptors, they either stimulate or block particular cellular signaling pathways that are implicated in various kinds of cancer. Naturally, all products in this section can also be found by their specific biological targets as listed in the sections of enzymes, receptors, transcription factors, proteins and/or signaling pathways. Besides the comprehensive set of compounds that targe cell signaling and oncology, selections of Axon Ligands™ have also been made for other research area's such as cardiovascular diseases, angiogenisis, epigenetics, stem cell research, among many others.
| Axon ID | Name | Description | From price | |
|---|---|---|---|---|
| 1683 | Y 27632 dihydrochloride | ROCK1 and ROCK2 inhibitor | €65.00 | |
| 2381 | WH-4-023 | Orally active src-family selective lck inhibitor | €90.00 | |
| 1562 | TWS 119 | GSK-3β inhibitor | €70.00 | |
| 1854 | TTP 22 | Inhibitor of Casein kinase 2 (CK2) | €105.00 | |
| 2560 | Tilfrinib | Brk inhibitor with antiproliferative activity in breast tumor cells | €95.00 | |
| 1535 | Thiazovivin | ROCK inhibitor and iPSC stimulator; Stem cell related | €90.00 | |
| 2010 | TDZD 8 | Selective and non-ATP-competitive inhibitor of GSK-3β | €90.00 | |
| 3232 | TAK-788 | Potent and selective EGFR and ErbB-2/HER2 tyrosine kinase inhibitor | €70.00 | |
| 5006 | Stem Cell CSD inhibitor Set | Set of CHIR 99021, SU5402, and DAPT, inhibitors of GSK-3, FGFR, and γ-secretase, resp. | €140.00 | |
| 2130 | Stem Cell Alternative 2i inhibitor Set | Set of SRC inhibitor CGP77675 (Axon 2097) and GSK-3 inhibitor CHIR99021 (Axon 1386) | €100.00 | |
| 5007 | Stem Cell 5i inhibitor Set | Set of five inhibitors for neural differentiation of human pluripotent stem cells. | €200.00 | |
| 5009 | Stem Cell 4i inhibitor Set | Set of Thiazovivin, SB 431542, PD 0325901, and CHIR 99021 (inhibitors of ROCK, TGF-β, MEK, and GSK-3 resp.) | €170.00 | |
| 2547 | SR 3029 | A potent, highly specific CK1δ/CK1ε inhibitor | €135.00 | |
| 1635 | Sotrastaurin | PKC inhibitor | €60.00 | |
| 1923 | SMI 4a | ATP-competitive and selective inhibitor of Pim kinases | €75.00 | |