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Research Areas

In ths section, by  far, most Axon Ligands™ are categorized as research tools that find their application in cell signaling and oncology. Targeting a multitude of specific enzymes and receptors, they either stimulate or block particular cellular signaling pathways that are implicated in various kinds of cancer. Naturally, all products in this section can also be found by their specific biological targets as listed in the sections of enzymes, receptors, transcription factors, proteins and/or signaling pathways. Besides the comprehensive set of compounds that targe cell signaling and oncology, selections of Axon Ligands™ have also been made for other research area's such as cardiovascular diseases, angiogenisis, epigenetics, stem cell research, among many others.

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Axon ID Name Description From price
2674 YUKA1 Selective inhibitor of KDM5A demethylase €125.00
2969 WM-1119 Highly potent and selective KAT6A inhibitor €125.00
2411 WDR5-0103 Inhibitor of WD40 repeat protein 5 (WDR5) and associated activity of H3K4 HMTase MLL €90.00
3114 Vorinostat HDAC inhibitor €45.00
1840 UNC 0646 Inhibitor of G9a/GLP Histone Lysine Methyltransferase €99.00
1889 UNC 0638 Inhibitor of G9a (EHMT2)/GLP (EHMT1) €85.00
1841 UNC 0631 Inhibitor of G9a/GLP Histone Lysine Methyltransferase €99.00
2418 UNC 0379 Substrate competitive inhibitor of the H4K20 HMTase SETD8 €125.00
1789 UNC 0224 Inhibitor of G9a HMTase €85.00
2518 UF 010 Class I selective HDAC inhibitor that inhibits cancer cell proliferation €60.00
2893 Tucidinostat Orally bioavailable HDAC inhibitor (1, 2, 3, 10 Selective) €95.00
2004 Tubastatin A hydrochloride Potent and selective HDAC6 inhibitor €95.00
2180 TMP 195 HDAC inhibitor (class IIA selective) €110.00
2996 TH 34 HDAC inhibitor (6, 8, 10 Selective) €120.00
2339 TH 1834 Tip60 histone acetyltransferase inhibitor €135.00

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Categories
  1. Angiogenesis
  2. Apoptosis
  3. CNS
  4. Cardiovascular
  5. Cell Cycle Regulation
  6. Cell Signaling & Oncology
  7. Diabetes & Metabolism
  8. Endocrinology
  9. Epigenetics
  10. Immunology
  11. Pain & Inflammation
  12. Stem Cell
  13. Miscellaneous
Filter by Endogenous Substrate
  1. 2-arachidonoyl glycerol (2-AG) (5)
  2. 3-phosphoglycerate (2)
  3. Acetylcholine (2)
  4. Ack1-AR-ATM signaling (3)
  5. Adenosine (1)
  6. ADP (1)
  7. Adrenaline, (Nor-) (3)
  8. AGE (1)
  9. Aggrecan (1)
  10. Alcohol (1)
  11. Aldose (2)
  12. Amyloids (13)
  13. Antigen (1)
  14. AP2 (2)
  15. Arginine (1)
  16. Arginine, L- (1)
  17. ATP (15)
  18. B-Cell Transformation (7)
  19. BCAA (1)
  20. C-Nap1,PP1,Nek2 (1)
  21. Calcium (2)
  22. cAMP (17)
  23. Carbondioxide (2)
  24. Caspase (4)
  25. Cation-Cl− cotransporters (CCCs) (1)
  26. CDK1 (1)
  27. Cell Cycle Regulation (1)
  28. Cellular Metabolic Homeostasis (1)
  29. Ceramide (1)
  30. cGMP (6)
  31. Chloride (3)
  32. Cholesterol (1)
  33. Choline (2)
  34. Citric acid (1)
  35. Collagen (1)
  36. Cortisone (1)
  37. Cyclin Dependent (CDK) (14)
  38. Cytoskeleton (25)
  39. Decaprenylphosphoryl-beta-D-ribofuranose (DPR) (2)
  40. Dehydroepiandrosterone,Androstenedione (1)
  41. Deoxyuridine monophosphate (dUMP) (2)
  42. Diacylglycerol (1)
  43. Dihydroorotate (2)
  44. DNA (3)
  45. DNA-damage response (5)
  46. DNA-RNA (123)
  47. dNTP (oxidized) (4)
  48. Dopamine (2)
  49. ECM-adhesion (7)
  50. EGF (14)
  51. EGF-VEGF (2)
  52. Eicosanoid epoxides (3)
  53. Endothelin; Non Selective (1)
  54. Ephrins (1)
  55. Farnesyl substrates (CaaX motif) (1)
  56. Fatty acid (Amides) (2)
  57. Fatty acid (Arachidonic acid) (13)
  58. Fatty acid (Linoleic acid) (1)
  59. Fatty acid (Stearic acid) (1)
  60. Fatty acids (3)
  61. FGF (9)
  62. FGF-VEGF (2)
  63. FLT3LG (4)
  64. Fructose 6-phosphate (2)
  65. G-Proteins (1)
  66. Gas6 (3)
  67. GDNF (2)
  68. Gluconeogenesis (1)
  69. Glucose (5)
  70. Glutathion (GSH) (1)
  71. Glycans (1)
  72. Glycine (3)
  73. Glycogen (1)
  74. Glycosides (3)
  75. Golgi apparatus (1)
  76. GTP (8)
  77. Hedgehog (2)
  78. Hemoglobin (2)
  79. HGF (8)
  80. HGF-VEGF (2)
  81. Histone
  82. HMG-CoA (1)
  83. Hypoxanthine (2)
  84. Hypoxia-signaling cascade (7)
  85. IGF1 (3)
  86. Innate immune system (1)
  87. Interleukin (6)
  88. Interleukin-8 (1)
  89. Isocitrate (4)
  90. IκB (7)
  91. JAK-STAT Pathway (15)
  92. Kinins (3)
  93. Kynurenine, L- (8)
  94. Lactate (1)
  95. LCCs, RyRs, and PLB (2)
  96. Lipid A precursor (3)
  97. LPC (1)
  98. LRP5 (1)
  99. Mannosidose (α form) (1)
  100. MAPK (44)
  101. MEK (12)
  102. Microtubules (6)
  103. Mono-amines (11)
  104. NADH (1)
  105. NADP+ (1)
  106. NADPH (2)
  107. NEDD8 (1)
  108. Neurotrophin (4)
  109. NF-κB Pathway (6)
  110. Nicotinamide D-ribonucleotide (3)
  111. Non Selective (49)
  112. Non Selective (ADF-cofilin) (4)
  113. Non Selective (Anions) (1)
  114. Non Selective (Arginine Sites Proteins) (8)
  115. Non Selective (Aspartate Peptide Bonds) (6)
  116. Non Selective (CHK2; p53) (8)
  117. Non Selective (COX substrates; Cannabinoids) (1)
  118. Non Selective (Cysteine Peptide Bonds) (3)
  119. Non Selective (Glucocorticoid) (1)
  120. Non Selective (glycosyl donors) (1)
  121. Non Selective (Histone; Survivin; Topo) (3)
  122. Non Selective (Histone; Survivin; Topo; TPX2) (5)
  123. Non Selective (Histone; Survivin; Topo; TPX2); JAK-STAT Pathway; Non Selective (Phosphorylation Substrates) (1)
  124. Non Selective (Ions; Na+Ca2+) (1)
  125. Non Selective (Ions; Na+H+) (1)
  126. Non Selective (LIM; p53; TPX2) (4)
  127. Non Selective (Lysine Sites Proteins) (1)
  128. Non Selective (Methionine Peptide Bonds) (1)
  129. Non Selective (Mitotic Spindle Checkpoint) (4)
  130. Non Selective (Noradrenaline; Dopamine) (1)
  131. Non Selective (Phosphorylation Substrates) (92)
  132. Non Selective (Phosphorylation Substrates); MAPK (1)
  133. Non Selective (Phosphorylation Substrates); MAPK; FGF-VEGF (1)
  134. Non Selective (Proline Peptide Bonds) (5)
  135. Non Selective (Ribosomal proteins) (5)
  136. Non Selective (Serine Peptide Bonds) (12)
  137. Non Selective (Serine-Threonine and Tyrosine Specific Phosphodiesters) (7)
  138. Non Selective (Serotonin; Noradrenaline) (10)
  139. Non Selective (Tripeptides) (1)
  140. Non Selective (Tyrosine Specific Phosphomonoesters) (8)
  141. Non Selective (Ubiquitin peptides) (22)
  142. NotchΔE-eGFP (1)
  143. p-Hydroxyphenyl-pyruvate (HPP),Phenylpyruvate (1)
  144. p53 (11)
  145. Palmitoyl-CoA; L-serine (1)
  146. PDGF-FGF-VEGF (2)
  147. Phosphatidylcholine (2)
  148. Phosphatidylinositol (67)
  149. Phospholipids (3)
  150. Potassium (5)
  151. PP2A (1)
  152. Prostaglandins (1)
  153. Protein Disulfide Isomerase (PDI) (1)
  154. Protein Rad21 (1)
  155. Pyruvate (2)
  156. Quorum Sensing (1)
  157. RAS proteins (3)
  158. Retrograde trafficking (1)
  159. Ribosome rescue (2)
  160. S-nitrosoglutathione (1)
  161. S-palmitoylated proteins (1)
  162. SCF-FLT3-PDGF (2)
  163. SCF-PDGF-FGF (1)
  164. SCF-PDGF-VEGF (6)
  165. SCF-VEGF (2)
  166. Securin,B type cyclins (1)
  167. Serotonin (8)
  168. Serpin (5)
  169. SIPA (1)
  170. Smad (2)
  171. Sonic Hedgehog (2)
  172. Sphingosine (4)
  173. Stem cells (iPSC) (1)
  174. Steroid (Androgens) (2)
  175. Steroid (Lanosterol 14-α) (4)
  176. Steroids (2)
  177. Succinic acid (1)
  178. Superoxide (1)
  179. T-Cell activity (1)
  180. T-Cell signaling (1)
  181. TGF-β (3)
  182. Thrombin (1)
  183. Thymidylate pathway (1)
  184. TNF-α (6)
  185. Triglycerides (8)
  186. Unfolded Protein Response (EIF2 Selective) (3)
  187. Unfolded Protein Response (Non Selective) (6)
  188. Uric acid (2)
  189. VEGF (12)
  190. Water (3)
  191. Wnt proteins (7)
  192. Xanthine (1)
  193. Zinc (1)
  194. β-Lactams (1)
Filter by Action
  1. Activator (1)
  2. Inhibitor
  3. Probe (1)
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