Research Areas
In ths section, by far, most Axon Ligands™ are categorized as research tools that find their application in cell signaling and oncology. Targeting a multitude of specific enzymes and receptors, they either stimulate or block particular cellular signaling pathways that are implicated in various kinds of cancer. Naturally, all products in this section can also be found by their specific biological targets as listed in the sections of enzymes, receptors, transcription factors, proteins and/or signaling pathways. Besides the comprehensive set of compounds that targe cell signaling and oncology, selections of Axon Ligands™ have also been made for other research area's such as cardiovascular diseases, angiogenisis, epigenetics, stem cell research, among many others.
| Axon ID | Name | Description | From price | |
|---|---|---|---|---|
| 1873 | Abiraterone | Inhibitor of CYP17A1 | €90.00 | |
| 1874 | Abiraterone acetate | Prodrug of Abiraterone; Inhibitor of CYP17A1 | €90.00 | |
| 2141 | ABT 199 | Potent, orally bioavailable BCL-2-selective inhibitor | €90.00 | |
| 1456 | AZD 0530 difumarate | Inhibitor of SRC and ABL tyrosine kinases | €70.00 | |
| 2153 | AZD 3463 | Potent inhibitor of ALK and IGF1R | €105.00 | |
| 1828 | BH3I 1 | Inhibitor of Bcl-2 family protein | €125.00 | |
| 3047 | BI-6C9 | Inhibitor of BID protein | €145.00 | |
| 2978 | Brigatinib | Potent, selective, and orally active anaplastic lymphoma kinase (ALK) inhibitor | €80.00 | |
| 2097 | CGP 77675 | Src Family kinase (SFK) inhibitor | €95.00 | |
| 1884 | CH 5424802 | Orally available and selective ALK inhibitor | €80.00 | |
| 1863 | CID 5951923 | Inhibitor of Krüppel-like factor 5 (KLF5) | €135.00 | |
| 3035 | Compound 10 |
Tool compound targeting the NFAT:AP-1 transcriptional complex on DNA. |
€150.00 | |
| 1654 | CP 100356 hydrochloride | P-gp inhibitor | €125.00 | |
| 3200 | DCLK1-IN-1 | Potent, selective and orally bioavailable DCLK1/2 inhibitor | Recently added | €140.00 |
| 2496 | Dimethylcelecoxib, 2,5- | Celecoxib analog with anti-tumor properties, lacking COX-2 inhibitory activity | €75.00 | |