Research Areas
In ths section, by far, most Axon Ligands™ are categorized as research tools that find their application in cell signaling and oncology. Targeting a multitude of specific enzymes and receptors, they either stimulate or block particular cellular signaling pathways that are implicated in various kinds of cancer. Naturally, all products in this section can also be found by their specific biological targets as listed in the sections of enzymes, receptors, transcription factors, proteins and/or signaling pathways. Besides the comprehensive set of compounds that targe cell signaling and oncology, selections of Axon Ligands™ have also been made for other research area's such as cardiovascular diseases, angiogenisis, epigenetics, stem cell research, among many others.
| Axon ID | Name | Description | From price | |
|---|---|---|---|---|
| 2611 | APS-2-79 | Inhibitor of KSR and oncogenic Ras signaling | €90.00 | |
| 1545 | AZ 628 | B-Raf and C-Raf protein kinase inhibitor | €80.00 | |
| 3067 | Belvarafenib | Orally bioavailable pan-Raf protein kinase inhibitor | €115.00 | |
| 1459 | GDC 0879 | B-Raf protein kinase inhibitor | €70.00 | |
| 1984 | GW 5074 | Brain-permeable inhibitor of c-Raf (in vitro) with activating effects in vivo | €85.00 | |
| 2590 | Locostatin | Non-toxic Raf kinase inhibitory protein (RKIP) inhibitor | €55.00 | |
| 1624 | PLX 4032 | B-Raf protein kinase inhibitor | €60.00 | |
| 1474 | PLX 4720 | B-Raf protein kinase inhibitor | €50.00 | |
| 2817 | RAF709 | Potent, selective, and efficacious B-Raf and C-Raf protein kinase inhibitor | €120.00 | |
| 2504 | SB 590885 | Selective inhibitor of B-Raf kinase with application in stem cell therapy | €95.00 | |
| 3351 | Sorafenib | Protein kinase inhibitor of Raf/MEK/ERK pathway | Recently added | €60.00 |
| 1397 | Sorafenib tosylate | Protein kinase inhibitor of Raf/MEK/ERK pathway | €80.00 | |