Research Areas
In ths section, by far, most Axon Ligands™ are categorized as research tools that find their application in cell signaling and oncology. Targeting a multitude of specific enzymes and receptors, they either stimulate or block particular cellular signaling pathways that are implicated in various kinds of cancer. Naturally, all products in this section can also be found by their specific biological targets as listed in the sections of enzymes, receptors, transcription factors, proteins and/or signaling pathways. Besides the comprehensive set of compounds that targe cell signaling and oncology, selections of Axon Ligands™ have also been made for other research area's such as cardiovascular diseases, angiogenisis, epigenetics, stem cell research, among many others.
| Axon ID | Name | Description | From price | |
|---|---|---|---|---|
| 2000 | CHIR 090 | Potent and selective LpxC inhibitor | €135.00 | |
| 1939 | LpxC inhibitor 1a | Potent antibacterial LpxC inhibitor (gram-negative infections) | €125.00 | |
| 2113 | PF 05081090 | LpxC inhibitor for treatment of gram-negative infections | €150.00 | |
Categories
- Filter by Endogenous Substrate
- 2-arachidonoyl glycerol (2-AG) (5)
- 3-phosphoglycerate (2)
- Acetylcholine (2)
- Ack1-AR-ATM signaling (3)
- Adenosine (1)
- ADP (1)
- Adrenaline, (Nor-) (3)
- AGE (1)
- Aggrecan (1)
- Alcohol (1)
- Aldose (2)
- Amyloids (13)
- Antigen (1)
- AP2 (2)
- Arginine (1)
- Arginine, L- (1)
- ATP (15)
- B-Cell Transformation (7)
- BCAA (1)
- C-Nap1,PP1,Nek2 (1)
- Calcium (2)
- cAMP (17)
- Carbondioxide (2)
- Caspase (4)
- Cation-Cl− cotransporters (CCCs) (1)
- CDK1 (1)
- Cell Cycle Regulation (1)
- Cellular Metabolic Homeostasis (1)
- Ceramide (1)
- cGMP (6)
- Chloride (3)
- Cholesterol (1)
- Choline (2)
- Citric acid (1)
- Collagen (1)
- Cortisone (1)
- Cyclin Dependent (CDK) (14)
- Cytoskeleton (25)
- Decaprenylphosphoryl-beta-D-ribofuranose (DPR) (2)
- Dehydroepiandrosterone,Androstenedione (1)
- Deoxyuridine monophosphate (dUMP) (2)
- Diacylglycerol (1)
- Dihydroorotate (2)
- DNA (3)
- DNA-damage response (5)
- DNA-RNA (122)
- dNTP (oxidized) (4)
- Dopamine (2)
- ECM-adhesion (7)
- EGF (14)
- EGF-VEGF (2)
- Eicosanoid epoxides (3)
- Endothelin; Non Selective (1)
- Ephrins (1)
- Farnesyl substrates (CaaX motif) (1)
- Fatty acid (Amides) (2)
- Fatty acid (Arachidonic acid) (13)
- Fatty acid (Linoleic acid) (1)
- Fatty acid (Stearic acid) (1)
- Fatty acids (3)
- FGF (9)
- FGF-VEGF (2)
- FLT3LG (4)
- Fructose 6-phosphate (2)
- G-Proteins (1)
- Gas6 (3)
- GDNF (2)
- Gluconeogenesis (1)
- Glucose (5)
- Glutathion (GSH) (1)
- Glycans (1)
- Glycine (3)
- Glycogen (1)
- Glycosides (3)
- Golgi apparatus (1)
- GTP (8)
- Hedgehog (2)
- Hemoglobin (2)
- HGF (8)
- HGF-VEGF (2)
- Histone (84)
- HMG-CoA (1)
- Hypoxanthine (2)
- Hypoxia-signaling cascade (7)
- IGF1 (3)
- Innate immune system (1)
- Interleukin (6)
- Interleukin-8 (1)
- Isocitrate (4)
- IκB (7)
- JAK-STAT Pathway (15)
- Kinins (3)
- Kynurenine, L- (8)
- Lactate (1)
- LCCs, RyRs, and PLB (2)
- Lipid A precursor
- LPC (1)
- LRP5 (1)
- Mannosidose (α form) (1)
- MAPK (44)
- MEK (12)
- Microtubules (6)
- Mono-amines (11)
- NADH (1)
- NADP+ (1)
- NADPH (2)
- NEDD8 (1)
- Neurotrophin (4)
- NF-κB Pathway (6)
- Nicotinamide D-ribonucleotide (3)
- Non Selective (49)
- Non Selective (ADF-cofilin) (4)
- Non Selective (Anions) (1)
- Non Selective (Arginine Sites Proteins) (8)
- Non Selective (Aspartate Peptide Bonds) (6)
- Non Selective (CHK2; p53) (8)
- Non Selective (COX substrates; Cannabinoids) (1)
- Non Selective (Cysteine Peptide Bonds) (3)
- Non Selective (Glucocorticoid) (1)
- Non Selective (glycosyl donors) (1)
- Non Selective (Histone; Survivin; Topo) (3)
- Non Selective (Histone; Survivin; Topo; TPX2) (5)
- Non Selective (Histone; Survivin; Topo; TPX2); JAK-STAT Pathway; Non Selective (Phosphorylation Substrates) (1)
- Non Selective (Ions; Na+Ca2+) (1)
- Non Selective (Ions; Na+H+) (1)
- Non Selective (LIM; p53; TPX2) (4)
- Non Selective (Lysine Sites Proteins) (1)
- Non Selective (Methionine Peptide Bonds) (1)
- Non Selective (Mitotic Spindle Checkpoint) (4)
- Non Selective (Noradrenaline; Dopamine) (1)
- Non Selective (Phosphorylation Substrates) (92)
- Non Selective (Phosphorylation Substrates); MAPK (1)
- Non Selective (Phosphorylation Substrates); MAPK; FGF-VEGF (1)
- Non Selective (Proline Peptide Bonds) (5)
- Non Selective (Ribosomal proteins) (5)
- Non Selective (Serine Peptide Bonds) (12)
- Non Selective (Serine-Threonine and Tyrosine Specific Phosphodiesters) (7)
- Non Selective (Serotonin; Noradrenaline) (10)
- Non Selective (Tripeptides) (1)
- Non Selective (Tyrosine Specific Phosphomonoesters) (8)
- Non Selective (Ubiquitin peptides) (22)
- NotchΔE-eGFP (1)
- p-Hydroxyphenyl-pyruvate (HPP),Phenylpyruvate (1)
- p53 (11)
- Palmitoyl-CoA; L-serine (1)
- PDGF-FGF-VEGF (2)
- Phosphatidylcholine (2)
- Phosphatidylinositol (67)
- Phospholipids (3)
- Potassium (5)
- PP2A (1)
- Prostaglandins (1)
- Protein Disulfide Isomerase (PDI) (1)
- Protein Rad21 (1)
- Pyruvate (2)
- Quorum Sensing (1)
- RAS proteins (3)
- Retrograde trafficking (1)
- Ribosome rescue (2)
- S-nitrosoglutathione (1)
- S-palmitoylated proteins (1)
- SCF-FLT3-PDGF (2)
- SCF-PDGF-FGF (1)
- SCF-PDGF-VEGF (6)
- SCF-VEGF (2)
- Securin,B type cyclins (1)
- Serotonin (7)
- Serpin (5)
- SIPA (1)
- Smad (2)
- Sonic Hedgehog (2)
- Sphingosine (4)
- Stem cells (iPSC) (1)
- Steroid (Androgens) (2)
- Steroid (Lanosterol 14-α) (4)
- Steroids (2)
- Succinic acid (1)
- Superoxide (1)
- T-Cell activity (1)
- T-Cell signaling (1)
- TGF-β (3)
- Thrombin (1)
- Thymidylate pathway (1)
- TNF-α (6)
- Triglycerides (8)
- Unfolded Protein Response (EIF2 Selective) (3)
- Unfolded Protein Response (Non Selective) (6)
- Uric acid (2)
- VEGF (12)
- Water (3)
- Wnt proteins (7)
- Xanthine (1)
- Zinc (1)
- β-Lactams (1)
- Filter by Action