Research Areas
In ths section, by far, most Axon Ligands™ are categorized as research tools that find their application in cell signaling and oncology. Targeting a multitude of specific enzymes and receptors, they either stimulate or block particular cellular signaling pathways that are implicated in various kinds of cancer. Naturally, all products in this section can also be found by their specific biological targets as listed in the sections of enzymes, receptors, transcription factors, proteins and/or signaling pathways. Besides the comprehensive set of compounds that targe cell signaling and oncology, selections of Axon Ligands™ have also been made for other research area's such as cardiovascular diseases, angiogenisis, epigenetics, stem cell research, among many others.
| Axon ID | Name | Description | From price | |
|---|---|---|---|---|
| 2830 | (R)-CE3F4 | Potent inhibitor of EPAC1 | €105.00 | |
| 2222 | 10058-F4 | c-Myc inhibitor inducing cell-cycle arrest at G0/G1 phase | €80.00 | |
| 2989 | 15-LOX-1 inhibitor i472 | Inhibitor of 15-lipoxygenase-1 (15-LOX-1) | €165.00 | |
| 2175 | 3PO | Inhibitor of HIF-1-induced PFKFB3, an enzyme with a key role in glycolysis. | €65.00 | |
| 1902 | 4μ8C | IRE1α inhibitor | €105.00 | |
| 2125 | 6,8-Bis(benzylthio)octanoic acid | Inhibitor of mitochondrial pyruvate dehydrogenase (PDH) complex | €105.00 | |
| 1909 | A 1070722 | Selective inhibitor of GSK-3 | €95.00 | |
| 1666 | A 357300 hydrochloride | MetAP2 inhibitor | €95.00 | |
| 1831 | A 66 | PI3K inhibitor (p110-α specific) | €95.00 | |
| 1698 | A 770041 | Orally active src-family selective lck inhibitor | €135.00 | |
| 2059 | A 922500 | Highly potent and selective diacylglycerol acyltransferase 1 (DGAT-1) inhibitor | €105.00 | |
| 2705 | A-196 | Potent and selective inhibitor of SUV4-20 | €105.00 | |
| 2720 | A-92 | Inhibitor of GCN2 (EIF2AK4) | €145.00 | |
| 1419 | AB 1010 | PDGFR, c-KIT and FGFR3 tyrosine kinase inhibitor | €70.00 | |
| 1873 | Abiraterone | Inhibitor of CYP17A1 | €90.00 | |