Research Areas

In this section, by  far, most Axon Ligands™ are categorized as research tools that find their application in cell signaling and oncology. Targeting a multitude of specific enzymes and receptors, they either stimulate or block particular cellular signaling pathways that are implicated in various kinds of cancer. Naturally, all products in this section can also be found by their specific biological targets as listed in the sections of enzymes, receptors, transcription factors, proteins and/or signaling pathways. Besides the comprehensive set of compounds that targe cell signaling and oncology, selections of Axon Ligands™ have also been made for other research area's such as cardiovascular diseases, angiogenisis, epigenetics, stem cell research, among many others.

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Axon ID Name Description From price
1066 N-Cyclopropyl-N-methyl-2-aminotetraline hydrobromide MAO inhibitor €95.00
3144 (+)-Blebbistatin Negative control of (±)-Blebbistatin as an inhibitor of class II myosins €90.00
1989 (+)-JQ-1

Potent and selective BET bromodomain inhibitor

€70.00
1730 (+)-Kifunensine α-mannosidase inhibitor €120.00
3074 (-)-Blebbistatin Selective inhibitor of class II myosins; Active enantiomer of (±)-Blebbistatin €90.00
3759 (aR)-RP-6306 (aR)-enantiomer of RP-6306 (Axon 3668); PKMYT1 inhibitor  Recently added €180.00
1229 (R)-(-)-Rolipram PDE4 inhibitor €110.00
2830 (R)-CE3F4 Potent inhibitor of EPAC1 €105.00
1432 (S)-(+)-Rolipram PDE4 inhibitor €115.00
2296 (S)-Crizotinib MTH1 inhibitor €85.00
2718 (±)-Blebbistatin Potent and specific inhibitor of class II myosins €95.00
1687 (±)-E-Homocamptothecin Potent topoisomerase I (Topo 1) inhibitor €120.00
2786 (±)-PH 797804 Inhibitor of p38α MAPK €115.00
2537 1,5-Isoquinolinediol PARP1 inhibitor and neuroprotective agent €50.00
2434 1-Deazaadenosine Adenosine deaminase (ADA) inhibitor with cytostatic activity in vitro €140.00
1892 1-NM-PP1 Potent tyrosine kinase inhibitor (TKI) of multiple targets (Src, Fyn, Abl, CDK, Trk) €95.00
2222 10058-F4 c-Myc inhibitor inducing cell-cycle arrest at G0/G1 phase €80.00
2989 15-LOX-1 inhibitor i472 Inhibitor of 15-lipoxygenase-1 (15-LOX-1) €165.00
3617 1R,3R-RSL3 (negative control) Negative control of 1S,3R-RSL3 as GPX4 inhibitor €90.00
3611 1S,3R-RSL3 GPX4 inhibitor; Ferroptosis inducer €90.00
2496 2,5-Dimethylcelecoxib Celecoxib analog with anti-tumor properties, lacking COX-2 inhibitory activity €75.00
3565 2-FPBA First potent, reversible and slow-onset inhibitor of mandelate racemase (MR) €50.00
1496 3-Aminobenzamide Competitive small molecule inhibitor of PARP €40.00
2175 3PO Inhibitor of HIF-1-induced PFKFB3, an enzyme with a key role in glycolysis. €65.00
3189 4-CPPC First potent, selective and reversible inhibitor of MIF-2 €135.00
1902 4μ8C IRE1α inhibitor €105.00
3419 5-Bromo-2’-deoxyuridine Thymidine analog; Labeling agent of cell proliferation €50.00
3476 5-NIdR Potent inhibitor of translesion DNA synthesis (TLS) €120.00
2125 6,8-Bis(benzylthio)octanoic acid Inhibitor of mitochondrial pyruvate dehydrogenase (PDH) complex €105.00
1909 A 1070722 Selective inhibitor of GSK-3 €95.00

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