Research Areas
In this section, by far, most Axon Ligands™ are categorized as research tools that find their application in cell signaling and oncology. Targeting a multitude of specific enzymes and receptors, they either stimulate or block particular cellular signaling pathways that are implicated in various kinds of cancer. Naturally, all products in this section can also be found by their specific biological targets as listed in the sections of enzymes, receptors, transcription factors, proteins and/or signaling pathways. Besides the comprehensive set of compounds that targe cell signaling and oncology, selections of Axon Ligands™ have also been made for other research area's such as cardiovascular diseases, angiogenisis, epigenetics, stem cell research, among many others.
| Axon ID | Name | Description | From price | |
|---|---|---|---|---|
| 1066 | N-Cyclopropyl-N-methyl-2-aminotetraline hydrobromide | MAO inhibitor | €95.00 | |
| 3144 | (+)-Blebbistatin | Negative control of (±)-Blebbistatin as an inhibitor of class II myosins | €90.00 | |
| 1989 | (+)-JQ-1 |
Potent and selective BET bromodomain inhibitor |
€70.00 | |
| 1730 | (+)-Kifunensine | α-mannosidase inhibitor | €120.00 | |
| 3074 | (-)-Blebbistatin | Selective inhibitor of class II myosins; Active enantiomer of (±)-Blebbistatin | €90.00 | |
| 3759 | (aR)-RP-6306 | (aR)-enantiomer of RP-6306 (Axon 3668); PKMYT1 inhibitor | Recently added | €180.00 |
| 1229 | (R)-(-)-Rolipram | PDE4 inhibitor | €110.00 | |
| 2830 | (R)-CE3F4 | Potent inhibitor of EPAC1 | €105.00 | |
| 1432 | (S)-(+)-Rolipram | PDE4 inhibitor | €115.00 | |
| 2296 | (S)-Crizotinib | MTH1 inhibitor | €85.00 | |
| 2718 | (±)-Blebbistatin | Potent and specific inhibitor of class II myosins | €95.00 | |
| 1687 | (±)-E-Homocamptothecin | Potent topoisomerase I (Topo 1) inhibitor | €120.00 | |
| 2786 | (±)-PH 797804 | Inhibitor of p38α MAPK | €115.00 | |
| 2537 | 1,5-Isoquinolinediol | PARP1 inhibitor and neuroprotective agent | €50.00 | |
| 2434 | 1-Deazaadenosine | Adenosine deaminase (ADA) inhibitor with cytostatic activity in vitro | €140.00 | |
| 1892 | 1-NM-PP1 | Potent tyrosine kinase inhibitor (TKI) of multiple targets (Src, Fyn, Abl, CDK, Trk) | €95.00 | |
| 2222 | 10058-F4 | c-Myc inhibitor inducing cell-cycle arrest at G0/G1 phase | €80.00 | |
| 2989 | 15-LOX-1 inhibitor i472 | Inhibitor of 15-lipoxygenase-1 (15-LOX-1) | €165.00 | |
| 3617 | 1R,3R-RSL3 (negative control) | Negative control of 1S,3R-RSL3 as GPX4 inhibitor | €90.00 | |
| 3611 | 1S,3R-RSL3 | GPX4 inhibitor; Ferroptosis inducer | €90.00 | |
| 2496 | 2,5-Dimethylcelecoxib | Celecoxib analog with anti-tumor properties, lacking COX-2 inhibitory activity | €75.00 | |
| 3565 | 2-FPBA | First potent, reversible and slow-onset inhibitor of mandelate racemase (MR) | €50.00 | |
| 1496 | 3-Aminobenzamide | Competitive small molecule inhibitor of PARP | €40.00 | |
| 2175 | 3PO | Inhibitor of HIF-1-induced PFKFB3, an enzyme with a key role in glycolysis. | €65.00 | |
| 3189 | 4-CPPC | First potent, selective and reversible inhibitor of MIF-2 | €135.00 | |
| 1902 | 4μ8C | IRE1α inhibitor | €105.00 | |
| 3419 | 5-Bromo-2’-deoxyuridine | Thymidine analog; Labeling agent of cell proliferation | €50.00 | |
| 3476 | 5-NIdR | Potent inhibitor of translesion DNA synthesis (TLS) | €120.00 | |
| 2125 | 6,8-Bis(benzylthio)octanoic acid | Inhibitor of mitochondrial pyruvate dehydrogenase (PDH) complex | €105.00 | |
| 1909 | A 1070722 | Selective inhibitor of GSK-3 | €95.00 | |