Research Areas

In this section, by  far, most Axon Ligands™ are categorized as research tools that find their application in cell signaling and oncology. Targeting a multitude of specific enzymes and receptors, they either stimulate or block particular cellular signaling pathways that are implicated in various kinds of cancer. Naturally, all products in this section can also be found by their specific biological targets as listed in the sections of enzymes, receptors, transcription factors, proteins and/or signaling pathways. Besides the comprehensive set of compounds that targe cell signaling and oncology, selections of Axon Ligands™ have also been made for other research area's such as cardiovascular diseases, angiogenisis, epigenetics, stem cell research, among many others.

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Axon ID Name Description From price
2534 (+)-Azasetron hydrochloride 5-HT3 antagonist €135.00
2467 (+)-ITD-1 Selective inhibitor of TGFβ/Smad signaling that promotes cardiogenesis €165.00
1107 (+)-MDL 105725 5-HT2A antagonist €130.00
2535 (-)-Azasetron hydrochloride 5-HT3 antagonist €135.00
1108 (-)-MDL 105725 5-HT2A antagonist Inquire
1359 (-)-WAY 100135 dihydrochloride 5-HT1A antagonist €95.00
1095 (R)-(-)-LY 426965 dihydrochloride 5-HT1A antagonist €115.00
2784 (R)-(-)-N-Desmethyl-PK 11195 Radioligand precursor of the benzodiazepine antagonist (R)-(-)-PK 11195 €145.00
2785 (R)-(-)-PK 11195 Benzodiazepine antagonist. €125.00
1007 (R)-5-Hydroxy-DPAT hydrobromide D2 antagonist €145.00
3435 (S)-VU0637120 First-in-class, selective neuropeptide Y4 receptor allosteric antagonist €120.00
1341 (S)-WAY 100135 dihydrochloride 5-HT1A antagonist €95.00
1224 (±)-LY 367385 mGluR1a antagonist €80.00
1093 (±)-LY 426965 dihydrochloride 5-HT1A antagonist €115.00
1106 (±)-MDL 105725 5-HT2A antagonist €145.00
1575 5-HT6 antagonist 29 Selective brain penetrant 5-HT6 receptor antagonist €90.00
2944 A 381393 Potent, brain-penetrant, selective antagonist of the dopamine D4 receptor €125.00
1744 A 77-01 TGF-βR 1 inhibitor; ALK 5 inhibitor €80.00
1816 A 784168 TRPV1 receptor antagonist €95.00
2182 A 804598 Potent and selective P2X7 antagonist €125.00
1421 A 83-01 TGF-βR 1 inhibitor; ALK 5 inhibitor €70.00
2155 A 841720 Non-competitive mGluR1 antagonist €85.00
1990 A 943931 H4 antagonist €70.00
1179 A1B1 hydrochloride CCR1 antagonist €125.00
1504 ABT 102 TRPV1 antagonist €90.00
1510 ABT 239 tartrate H3 antagonist/inverse agonist €120.00
2388 Adomeglivant Potent, selective, orally administered, and competitive human glucagon receptor (GR) antagonist €95.00
1097 Alosetron hydrochloride 5-HT3 antagonist €85.00
2062 Alprostadil Prostaglandin EP (1-4) receptor antagonist €125.00
2367 AM 095 (parent compound) Novel potent and selective LPA1 antagonist €125.00

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