CNS

The human nervous system is divided into the central nervous system (CNS) and the peripheral nervous system (PNS). The CNS, in turn, is divided into the brain and the spinal cord, which lie in the cranial cavity of the skull and the vertebral canal, respectively. The CNS and the PNS, acting in concert, integrate sensory information and control motor and cognitive functions. Based on its functions, the CNS can be divided into three main functional components: the sensory system, the motor system, and homeostatic and higher brain functions. Cell signaling throughout the CNS occurs by means of neurotransmitters or ions of various kinds interacting at membrane bound receptors and ion channels that, in turn, send the signal through second messenger systems to different compartments of the cell. Malfunctions of the CNS can cause numerous diseases and disorders such as Alzheimer's and Parkinson's disease, multiple sclerosis (MS), anxiety, schizophrenia, and many others. Although many of these failures of the CNS appear to be age related, some occur already in a very early stage of development of the organism, or may even be genetically inherited. The prevention and treatment of neurological disorders represents one of the most difficult and challenging goals of modern medical research.

15 Item(s)

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Axon ID Name Description From price
1188 Adenosine amine congener Adenosine A1 agonist €125.00
2317 BAY 60-6583 Potent and highly selective A2BAR (Adenosine) agonist €125.00
1319 CGS 21680 hydrochloride Adenosine A2A agonist €95.00
1190 Chloroadenosine, 2- Adenosine A1 and A2A agonist €65.00
1287 GR 79236 Adenosine A1 agonist €120.00
1423 KW 6002 Adenosine A2A antagonist €85.00
2076 MRS 1523 Adenosine A3 receptor antagonist €120.00
1603 Rolofylline Adenosine A1 antagonist €85.00
1852 Rolofylline metabolite M1-cis Adenosine A1 antagonist €105.00
1851 Rolofylline metabolite M1-trans Adenosine A1 antagonist €105.00
1264 SCH 442416 Adenosine A2A antagonist €90.00
2283 SCH 442416, Desmethyl Radioligand precursor of the adenosine A2A antagonist SCH 442416 €300.00
1253 SCH 58261 Adenosine A2A antagonist €90.00
1265 SDZ-WAG 994 Adenosine A1 agonist €125.00
1193 UK 432097 Adenosine A2A agonist €135.00

15 Item(s)

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