CNS

The human nervous system is divided into the central nervous system (CNS) and the peripheral nervous system (PNS). The CNS, in turn, is divided into the brain and the spinal cord, which lie in the cranial cavity of the skull and the vertebral canal, respectively. The CNS and the PNS, acting in concert, integrate sensory information and control motor and cognitive functions. Based on its functions, the CNS can be divided into three main functional components: the sensory system, the motor system, and homeostatic and higher brain functions. Cell signaling throughout the CNS occurs by means of neurotransmitters or ions of various kinds interacting at membrane bound receptors and ion channels that, in turn, send the signal through second messenger systems to different compartments of the cell. Malfunctions of the CNS can cause numerous diseases and disorders such as Alzheimer's and Parkinson's disease, multiple sclerosis (MS), anxiety, schizophrenia, and many others. Although many of these failures of the CNS appear to be age related, some occur already in a very early stage of development of the organism, or may even be genetically inherited. The prevention and treatment of neurological disorders represents one of the most difficult and challenging goals of modern medical research.

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Axon ID Name Description From price
2811 25CN-NBOH hydrochloride Selective brain penetrant 5-HT2A receptor agonist €145.00
1575 5-HT6 antagonist 29 Selective brain penetrant 5-HT6 receptor antagonist €90.00
1097 Alosetron hydrochloride 5-HT3 antagonist €85.00
1058 Aminotetraline hydrochloride, (R)-(+)-8-Methoxy-2- Building Block; 5-HT1A agonist Inquire
1059 Aminotetraline hydrochloride, (S)-(-)-8-Methoxy-2- Building Block; 5-HT1A agonist Inquire
1057 Aminotetraline hydrochloride, 8-Methoxy-2- Building Block; 5-HT1A agonist Inquire
1462 Azaphen Antidepressant €105.00
1096 Azasetron hydrochloride 5-HT3 antagonist €90.00
2534 Azasetron hydrochloride, (+)- 5-HT3 antagonist €135.00
2535 Azasetron hydrochloride, (-)- 5-HT3 antagonist €135.00
2353 Blonanserin Potent dopamine D2 and serotonin 5-HT2 antagonist €65.00
2335 Brexpiprazole dihydrochloride Drug candidate with high affinity for 5-HT1A, 5-HT2A, D2L, α1B, and α2C-adrenergic receptors €135.00
1257 BTS 54-505 5-HT uptake inhibitor €85.00
1995 Buspirone hydrochloride 5-HT1A partial agonist €50.00
1206 CGS 12066B 5-HT1B agonist €75.00

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