CNS

The human nervous system is divided into the central nervous system (CNS) and the peripheral nervous system (PNS). The CNS, in turn, is divided into the brain and the spinal cord, which lie in the cranial cavity of the skull and the vertebral canal, respectively. The CNS and the PNS, acting in concert, integrate sensory information and control motor and cognitive functions. Based on its functions, the CNS can be divided into three main functional components: the sensory system, the motor system, and homeostatic and higher brain functions. Cell signaling throughout the CNS occurs by means of neurotransmitters or ions of various kinds interacting at membrane bound receptors and ion channels that, in turn, send the signal through second messenger systems to different compartments of the cell. Malfunctions of the CNS can cause numerous diseases and disorders such as Alzheimer's and Parkinson's disease, multiple sclerosis (MS), anxiety, schizophrenia, and many others. Although many of these failures of the CNS appear to be age related, some occur already in a very early stage of development of the organism, or may even be genetically inherited. The prevention and treatment of neurological disorders represents one of the most difficult and challenging goals of modern medical research.

20 Item(s)

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Axon ID Name Description From price
1261 4-Methylhistamine dihydrochloride H4 agonist €120.00
1990 A 943931 H4 antagonist €70.00
1510 ABT 239 tartrate H3 antagonist/inverse agonist €120.00
1207 Amthamine dihydrobromide H2 agonist €90.00
3373 Cetirizine dihydrochloride Highly selective H1 antagonist €50.00
1993 Ciproxifan maleate H3 antagonist €90.00
1209 Clobenpropit dihydrobromide H3 antagonist €90.00
3659 Desloratadine Potent and selective H1 antagonist €60.00
1324 Dimaprit dihydrochloride H2 agonist €45.00
1445 Dimebon Alzheimer's disease therapeutic €60.00
1453 Fexofenadine hydrochloride H1 antagonist €55.00
1325 Imetit dihydrobromide H3 agonist €80.00
1326 Immepip dihydrobromide H3 and H4 agonist €105.00
1327 Immethridine dihydrobromide H3 agonist €85.00
1328 Iodophenpropit dihydrobromide H3 antagonist €130.00
1307 JNJ 10191584 H4 antagonist €80.00
1306 JNJ 7777120 H4 antagonist €80.00
1299 Loratadine H1 antagonist €70.00
1458 PF 3654746 H3 antagonist €100.00
2126 VUF 10460 H4 agonist €95.00

20 Item(s)

per page
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