CNS

The human nervous system is divided into the central nervous system (CNS) and the peripheral nervous system (PNS). The CNS, in turn, is divided into the brain and the spinal cord, which lie in the cranial cavity of the skull and the vertebral canal, respectively. The CNS and the PNS, acting in concert, integrate sensory information and control motor and cognitive functions. Based on its functions, the CNS can be divided into three main functional components: the sensory system, the motor system, and homeostatic and higher brain functions. Cell signaling throughout the CNS occurs by means of neurotransmitters or ions of various kinds interacting at membrane bound receptors and ion channels that, in turn, send the signal through second messenger systems to different compartments of the cell. Malfunctions of the CNS can cause numerous diseases and disorders such as Alzheimer's and Parkinson's disease, multiple sclerosis (MS), anxiety, schizophrenia, and many others. Although many of these failures of the CNS appear to be age related, some occur already in a very early stage of development of the organism, or may even be genetically inherited. The prevention and treatment of neurological disorders represents one of the most difficult and challenging goals of modern medical research.

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Axon ID Name Description From price
2616 ZQ-16 Potent and selective GPR84 agonist that induces phosphorylation of ERK1/2 €95.00
1197 Zopiclone Benzodiazepine agonist €75.00
1446 Ziprasidone hydrochloride Atypical antipsychotic €50.00
2261 ZD 9379 Antagonist of the glycine site on the NMDA receptor complex €95.00
2543 ZCZ 011 Brain penetrant CB1 positive allosteric modulator (PAM) €125.00
1216 Zardaverine PDE3 and PDE4 inhibitor €75.00
1273 Zamifenacin fumarate Muscarinic M3 antagonist €115.00
1646 Zaleplon GABAA-α1 agonist €65.00
2159 Z-VAD-FMK Pan-caspase inhibitor with in vivo activity €110.00
1312 YM 90K hydrochloride AMPA antagonist €85.00
1259 YM 298198 hydrochloride, desmethyl mGluR1 antagonist €105.00
1260 YM 298198 hydrochloride mGluR1 antagonist €95.00
2056 XEN 907 Sodium channel blocker (voltage-gated Nav1.7) €135.00
1305 XE 991 dihydrochloride KCNQ channel and M-current blocker €90.00
1987 XE 991 KCNQ channel and M-current blocker €90.00

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