CNS

The human nervous system is divided into the central nervous system (CNS) and the peripheral nervous system (PNS). The CNS, in turn, is divided into the brain and the spinal cord, which lie in the cranial cavity of the skull and the vertebral canal, respectively. The CNS and the PNS, acting in concert, integrate sensory information and control motor and cognitive functions. Based on its functions, the CNS can be divided into three main functional components: the sensory system, the motor system, and homeostatic and higher brain functions. Cell signaling throughout the CNS occurs by means of neurotransmitters or ions of various kinds interacting at membrane bound receptors and ion channels that, in turn, send the signal through second messenger systems to different compartments of the cell. Malfunctions of the CNS can cause numerous diseases and disorders such as Alzheimer's and Parkinson's disease, multiple sclerosis (MS), anxiety, schizophrenia, and many others. Although many of these failures of the CNS appear to be age related, some occur already in a very early stage of development of the organism, or may even be genetically inherited. The prevention and treatment of neurological disorders represents one of the most difficult and challenging goals of modern medical research.

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Axon ID Name Description From price
1518 Timolol maleate β1 adrenergic antagonist €105.00
2579 TAK 259 Selective and orally active α1D adrenoceptor antagonist €95.00
1290 ST 91 α2 adrenoceptor agonist €80.00
1240 Reboxetine mesylate Noradrenaline reuptake inhibitor (NARI) €105.00
2040 Prazosin hydrochloride Peripherally acting α1 adrenoceptor antagonist €50.00
1296 Modafinil α1 adrenoceptor agonist €55.00
2414 Mirabegron Highly selective and orally active agonist of the human β3-adrenoceptor €125.00
3066 Medetomidine hydrochloride Potent and selective α2 adrenoceptor agonist €70.00
1155 Efaroxan hydrochloride α2 adrenoceptor antagonist €65.00
3065 Dexmedetomidine hydrochloride Selective α2 adrenoceptor agonist €75.00
3044 Clonidine hydrochloride α2 adrenoceptor agonist €60.00
1159 Celiprolol hydrochloride β1 antagonist €135.00
1157 Bromobuterol β2 agonist €85.00
1555 Brimonidine tartrate α2 adrenoceptor agonist €95.00
1154 B-HT 933 dihydrochloride α2 adrenoceptor agonist €115.00

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