CNS

The human nervous system is divided into the central nervous system (CNS) and the peripheral nervous system (PNS). The CNS, in turn, is divided into the brain and the spinal cord, which lie in the cranial cavity of the skull and the vertebral canal, respectively. The CNS and the PNS, acting in concert, integrate sensory information and control motor and cognitive functions. Based on its functions, the CNS can be divided into three main functional components: the sensory system, the motor system, and homeostatic and higher brain functions. Cell signaling throughout the CNS occurs by means of neurotransmitters or ions of various kinds interacting at membrane bound receptors and ion channels that, in turn, send the signal through second messenger systems to different compartments of the cell. Malfunctions of the CNS can cause numerous diseases and disorders such as Alzheimer's and Parkinson's disease, multiple sclerosis (MS), anxiety, schizophrenia, and many others. Although many of these failures of the CNS appear to be age related, some occur already in a very early stage of development of the organism, or may even be genetically inherited. The prevention and treatment of neurological disorders represents one of the most difficult and challenging goals of modern medical research.

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Axon ID Name Description From price
1710 WAY 208466 dihydrochloride Potent and selective 5-HT6 receptor agonist €120.00
1341 WAY 100135 dihydrochloride, (S)- 5-HT1A antagonist €95.00
1359 WAY 100135 dihydrochloride, (-)- 5-HT1A antagonist €95.00
1360 WAY 100135 dihydrochloride 5-HT1A antagonist €75.00
2889 VA012 Positive allosteric modulator (PAM) of 5-HT2C receptor €105.00
1285 U 92016A 5-HT1A agonist €95.00
2060 TD 5108 Selective 5-HT4 receptor agonist €135.00
2715 SUVN-502 Selective, orally active, brain-penetrant 5-HT6 receptor antagonist €105.00
1519 Sunepitron hydrochloride Anxiolytic and antidepressant drug €140.00
1352 Sumatriptan succinate 5-HT1B and 5-HT1D agonist €85.00
1927 SGS 518 Selective 5-HT6 antagonist €90.00
1300 Sertraline hydrochloride SSRI; Antidepressant €85.00
1141 Sertindole 5-HT2, D2 and α1 adrenoceptor antagonist €82.00
1382 SB 742457 hydrochloride 5-HT6 antagonist €80.00
1469 SB 699551A 5-HT5A antagonist €95.00

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