Cell Cycle Regulation

This class of Axon Ligands™ consists of compounds that affect the processes occurring in eukaryatic cells responsible for cell replication. Cells that are not in a quiescent state exist in either 1 of the 4 known stages of cell duplication: G1, S, G2, or M. The first 3 stages (G1, S, G2) together form the so-called “Interphase” during which the cell increases in size, accumulates required nutrients, and replicates the DNA in the cell nucleus. The correctness of these complex processes is evaluated at checkpoints at the end of each of the individual stages. If all checkpoints are passed successfully, the cell cycle enters the stage of the actual cell division/mitosis[1]. During mitoses, again, 4 distinct phases can be discriminated as pro-, meta-, ana-, and telephase.

[1] J.M. Berg, J.L. Tymoczko, L. Stryer. Biochemistry, 2002, 5th edition.New York. W. H. Freeman.

7 Item(s)

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Axon ID Name Description From price
2251 Apoptozole Inhibitor of ATPase activity of Hsc70 and Hsp70 €95.00
1543 CNF 2024 Hsp90 inhibitor €80.00
2703 ML346 Hsp70 activator €125.00
1542 NVP-AUY922 Hsp90 inhibitor €75.00
1856 PU-H71 trihydrochloride Hsp90 inhibitor €105.00
1968 STA 9090 Hsp90 inhibitor €105.00
1608 VER 155008 Hsp70 inhibitor €95.00

7 Item(s)

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