Cardiovascular

The circulatory system is a vast network of organs and vessels that is responsible for the flow of blood, nutrients, oxygen and other gases, and hormones to and from cells. The system consists of three independent systems that work together: the heart (cardiovascular), lungs (pulmonary), and arteries, veins, coronary and portal vessels (systemic). Together, the heart, blood, and blood vessels make up the cardiovascular component of the circulatory system. It includes the pulmonary circulation, a "loop" through the lungs where blood is oxygenated. It also incorporates the systemic circulation, which runs through the rest of the body to provide oxygenated blood. 
Because of its vastness and critical nature, the circulatory system is one of the systems of the body most prone to disease. Disorders of this system are the leading cause of death among adults in the majority of countries world-wide, arteriosclerosis being one of  the most common diseases. It is characterized by  fatty deposits in the arteries that cause the walls to stiffen and thicken the walls, and may result in restricted blood flow and ischemia. This may result in symptoms such as angina and dyspnea, necrosis, and ultimately in heart attack or stroke. Hypertension, another circulatory is disease, causes the heart to work harder and can lead to complications as a heart attack, a stroke, or kidney failure. Abnormal blood lipid levels, that is high total cholesterol, high levels of triglycerides, high levels of low-density lipoprotein or low levels of high-density lipoprotein (HDL) cholesterol all increase the risk of heart disease and stroke, and are of particular interest of modern research. 
Besides changing food intake habits of patients suffering from cardiovascular diseases, in combination with the stimulation to increase physical exercise, special medication may also modify a patients blood lipid profile and prevent the person from developing life threatening circulatory diseases.

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Axon ID Name Description From price
1190 2-Chloroadenosine Adenosine A1 and A2A agonist €65.00
1188 Adenosine amine congener Adenosine A1 agonist €125.00
2275 AdipoRon Orally active small-molecule AdipoR agonist €80.00
1207 Amthamine dihydrobromide H2 agonist €75.00
3386 AVE0991 Selective and orally active Mas receptor agonist €150.00
1154 B-HT 933 dihydrochloride α2 adrenoceptor agonist €115.00
2317 BAY 60-6583 Potent and highly selective A2BAR (Adenosine) agonist €125.00
1157 Bromobuterol β2 agonist €85.00
1319 CGS 21680 hydrochloride Adenosine A2A agonist €95.00
2015 CP 945598 CB1 antagonist €135.00
2119 CP 945598 hydrochloride CB1 antagonist €135.00
1324 Dimaprit dihydrochloride H2 agonist €45.00
1445 Dimebon Alzheimer's disease therapeutic €60.00
2050 Eletriptan hydrobromide Selective 5-HT1B/1D receptor agonist €90.00
2146 Fedovapagon Selective vasopressin V2 receptor agonist €120.00

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