Androgen (AR)

The third class of nuclear receptors (Nuclear, Class 3, Estrogen Receptor-like) includes estrogen and estrogen-related receptors (ER), as well as the 3-ketosteroid receptors (progesterone (PR), androgen (AR), gluco- and mineralocorticoid (GR and MR, respectively) receptors).
Androgens ((dihydro-) and testosterone) are the male sex hormones that belong to the steroid hormone family. They are mainly produced in testes, ovaries and adrenals. In early life, testicular androgens induce differentiation processes that lead to the development of the male phenotype. During adulthood, androgens remain essential for the maintenance of the male reproductive function, as well as a number of gender-dependent parameters like bone and muscle mass, hair growth and behavior. The androgen receptor (AR), holds a specific position within the group of steroid receptors, since several selective androgen response elements (selAREs) have been described that are not recognized by the other 3-ketosteroid receptors[1].


[1] Diverse roles of androgen receptor (AR) domains in AR-mediated signaling. F. Claessens et al. Nucl Recept Signal. 2008, 6, e008. 
 

4 Item(s)

per page
Axon ID Name Description From price
1979 ARN 509 Antagonist of androgen receptor (AR) €95.00
1613 MDV 3100 Androgen receptor (AR) antagonist €70.00
1532 RD 162 Androgen receptor (AR) antagonist €125.00
1680 RU 58841 Androgen receptor (AR) antagonist €80.00

4 Item(s)

per page
Please wait...