Neurotransmitters
Intercellular communication in the central nervous system requires the precise control of the duration and the intensity of neurotransmitter action at the specific receptors. After they have been released at the synapse, neurotransmitters activate pre- and/or postsynaptic receptors. To terminate synaptic transmission, neurotransmitters can, in turn, be inactivated by either enzymatic degradation or active transport into neuronal and/or glial cells by neurotransmitter transporters[1]. Reuptake inhibitors of neurotransmitters have a direct effect on extracellular concentrations of neurotransmitters in the synapses, and therefore influence neurotransmission. Axon Medchem offers inhibitors for a wide range of (monoamine) reuptake inhibitors of high quality.
[1] Neurotransmitter Transporters in the Central Nervous System. J. Masson, C. Sagné, M. Hamon, S. El Mestikawy. Pharm. Rev. 1999, 51, 439-464.
Axon ID | Name | Description | From price | |
---|---|---|---|---|
1722 | Deshydroxy Venlafaxine HCl | Metabolite of Venlafaxine; SNRI | €95.00 | |
3555 | Desvenlafaxine hydrochloride | Metabolite of Venlafaxine; SNRI | €70.00 | |
1726 | Dinorvenlafaxine | Metabolite of Venlafaxine; SNRI | €75.00 | |
3128 | Levomilnacipran hydrochloride | SNRI | €120.00 | |
3578 | O-Desmethylvenlafaxine | Metabolite of Venlafaxine; SNRI | €70.00 | |
2116 | O-Desmethylvenlafaxine succinate | Metabolite of Venlafaxine; SNRI | €90.00 | |
1720 | R-(-)-O-Desmethylvenlafaxine | Metabolite of Venlafaxine; SNRI | €125.00 | |
1721 | S-(+)-O-Desmethylvenlafaxine | Metabolite of Venlafaxine; SNRI | €125.00 | |
1727 | Venlafaxine hydrochloride | SNRI | €60.00 | |
1724 | WY 45494 hydrochloride | Metabolite of Venlafaxine; SNRI | €75.00 | |
1723 | WY 45960 hydrochloride | Metabolite of Venlafaxine; SNRI | €95.00 | |
1725 | WY 46689 | Metabolite of Venlafaxine; SNRI | €75.00 |