GlyT

Intercellular communication in the central nervous system requires the precise control of the duration and the intensity of neurotransmitter action at the specific receptors. After they have been released at the synapse, neurotransmitters activate pre- and/or postsynaptic receptors. To terminate synaptic transmission, neurotransmitters can, in turn, be inactivated by either enzymatic degradation or active transport into neuronal and/or glial cells by neurotransmitter transporters[1]. Reuptake inhibitors of neurotransmitters have a direct effect on extracellular concentrations of neurotransmitters in the synapses, and therefore influence neurotransmission. Axon Medchem offers inhibitors for a wide range of (monoamine) reuptake inhibitors of high quality.


[1] Neurotransmitter Transporters in the Central Nervous System. J. Masson, C. Sagné, M. Hamon, S. El Mestikawy. Pharm. Rev. 1999, 51, 439-464.

4 Item(s)

per page
Axon ID Name Description From price
1238 ALX 5407 hydrochloride GlyT-1 inhibitor €140.00
4201 Iclepertin Potent, selective and orally active GlyT-1 inhibitor €240.00
1563 ORG 25935 GlyT-1 inhibitor €90.00
1549 SSR 504734 GlyT-1 inhibitor €110.00

4 Item(s)

per page
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