Transferases

A transferase is an enzyme that catalyzes the transfer of a functional group from one molecule to another. As such, protein kinases are a significant member of this family of enzymes, being capable of transferring phosphorus-containing groups (phosphate) from a donor (usually adenosine triphosphate (ATP)) to specific amino acid residues with a free hydroxyl group of an acceptor in a covalent way[1]. As within the class of oxidoreductases, the class of transferases is divided into  subclasses, based on the functional groups the enzymes transfer and the substrate specificity.


[1] The Cell: A Molecular Approach. 2nd edition. Cooper GM. Sunderland (MA): Sinauer Associates; 2000.

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Axon ID Name Description From price
2345 AZ 20 Potent, orally active and selective inhibitor of ATR protein kinase €105.00
3134 AZD6738 Potent, selective, orally active and bioavailable ATR kinase inhibitor €110.00
2918 BAY 1895344 Potent, orally available and highly selective inhibitor of ATR protein kinase €100.00
1893 VE 821 Inhibitor of the DNA damage response kinase ATR €80.00
2452 VE 822 Selective ATR inhibitor that decreases survival of pancreatic cancer cells €110.00

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