Transferases

A transferase is an enzyme that catalyzes the transfer of a functional group from one molecule to another. As such, protein kinases are a significant member of this family of enzymes, being capable of transferring phosphorus-containing groups (phosphate) from a donor (usually adenosine triphosphate (ATP)) to specific amino acid residues with a free hydroxyl group of an acceptor in a covalent way[1]. As within the class of oxidoreductases, the class of transferases is divided into  subclasses, based on the functional groups the enzymes transfer and the substrate specificity.


[1] The Cell: A Molecular Approach. 2nd edition. Cooper GM. Sunderland (MA): Sinauer Associates; 2000.

10 Item(s)

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Axon ID Name Description From price
2611 APS-2-79 Inhibitor of KSR and oncogenic Ras signaling €90.00
1545 AZ 628 B-Raf and C-Raf protein kinase inhibitor €80.00
1459 GDC 0879 B-Raf protein kinase inhibitor €70.00
1984 GW 5074 Brain-permeable inhibitor of c-Raf (in vitro) with activating effects in vivo €85.00
2590 Locostatin Non-toxic Raf kinase inhibitory protein (RKIP) inhibitor €55.00
1624 PLX 4032 B-Raf protein kinase inhibitor €75.00
1474 PLX 4720 B-Raf protein kinase inhibitor €60.00
2817 RAF709 Potent, selective, and efficacious B-Raf and C-Raf protein kinase inhibitor €120.00
2504 SB 590885 Selective inhibitor of B-Raf kinase with application in stem cell therapy €95.00
1397 Sorafenib tosylate Protein kinase inhibitor of Raf/MEK/ERK pathway €80.00

10 Item(s)

per page
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