Transferases

A transferase is an enzyme that catalyzes the transfer of a functional group from one molecule to another. As such, protein kinases are a significant member of this family of enzymes, being capable of transferring phosphorus-containing groups (phosphate) from a donor (usually adenosine triphosphate (ATP)) to specific amino acid residues with a free hydroxyl group of an acceptor in a covalent way[1]. As within the class of oxidoreductases, the class of transferases is divided into  subclasses, based on the functional groups the enzymes transfer and the substrate specificity.


[1] The Cell: A Molecular Approach. 2nd edition. Cooper GM. Sunderland (MA): Sinauer Associates; 2000.

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Axon ID Name Description From price
1291 AEG 3482 JNK inhibitor €85.00
2002 AS 602801 JNK inhibitor, which inhibited JNK1, JNK2 and JNK3 €120.00
2179 ASK1 Inhibitor 10 Potent, selective, and orally bioavailable ASK1 inhibitor €125.00
1516 AZD 6244 MEK1 and MEK2 inhibitor €70.00
1999 AZD 8330 MEK 1 inhibitor €105.00
1358 BIRB 796 MAPK inhibitor (p38 specific) €65.00
1808 BIX 02188 MEK5 inhibitor; ERK5 inhibitor €125.00
1809 BIX 02189 MEK5 inhibitor; ERK5 inhibitor €125.00
2856 BMS 582949 Inhibitor of p38α MAPK €155.00
2025 CC-401 ATP-competitive JNK inhibitor €115.00
2634 CC-930 Potent, selective, and orally active anti-fibrotic JNK inhibitor €105.00
1694 FR 180204 ERK inhibitor; AP-1 inhibitor €95.00
1761 GSK 1120212 MEK1 and MEK2 inhibitor €95.00
3059 GW 284543 hydrochloride Selective MEK5 inhibitor  Recently added €95.00
2949 JNK inhibitor VIII Selective, ATP-competitive, and cell-permeable JNK inhibitor €105.00

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