Transferases

A transferase is an enzyme that catalyzes the transfer of a functional group from one molecule to another. As such, protein kinases are a significant member of this family of enzymes, being capable of transferring phosphorus-containing groups (phosphate) from a donor (usually adenosine triphosphate (ATP)) to specific amino acid residues with a free hydroxyl group of an acceptor in a covalent way[1]. As within the class of oxidoreductases, the class of transferases is divided into  subclasses, based on the functional groups the enzymes transfer and the substrate specificity.


[1] The Cell: A Molecular Approach. 2nd edition. Cooper GM. Sunderland (MA): Sinauer Associates; 2000.

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Axon ID Name Description From price
2937 ZT-12-037-01 Specific STK19 inhibitor €125.00
1541 ZM 447439 Aurora B inhibitor €85.00
2445 ZLN 024 Allosteric activator of AMP-activated protein kinase (AMPK) €90.00
1254 Zebularine DNA methyltransferase inhibitor €95.00
1685 YS 49 Antiplatelet, antithrombotic €135.00
2675 YMU1 Selective inhibitor of human thymidylate kinase (hTMPK) €110.00
1683 Y 27632 dihydrochloride ROCK1 and ROCK2 inhibitor €65.00
1621 XMD 8-92 trifluoroacetate BMK1 inhibitor; ERK5 inhibitor €70.00
1846 XMD 8-92 BMK1 inhibitor; ERK5 inhibitor €70.00
2762 XMD 8-87 Potent and selective inhibitor of Ack1 tyrosine kinase (also known as TNK2) €95.00
1706 XL PI3K/mTOR inhibitor Dual PI3K and mTOR kinase inhibitor €125.00
2268 XL 413 hydrochloride Potent, selective and orally bioavailable CDC7 inhibitor €120.00
2951 XL 388 Highly potent, selective, ATP-competitive, and orally bioavailable mTOR inhibitor €125.00
2231 XL 019 JAK2 inhibitor €100.00
1527 XAV 939 Tankyrase (TNKS) inhibitor €80.00

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