Methyltransferases

Over the recent years, Axon Medchem has significantly expanded its product line in the field of oncology research tools. Among them, the DNA methyltransferase and histone methyltransferase inhibitors comprise a small, yet significant selection of this set of tools. In view of the recent focus in biology on epigenetics, and DNA methylation being the best-known epigenetic marker (see also section: Axon Ligands™ for Epigenetic Research), we aim to be up front with these products to serve researchers in their objective to develop new drugs for the treatment of cancers and study the mechanisms involved in gene expression[1].


[1] Epigenetics in Cancer. M. Esteller.N Engl J Med 2008; 358, 1148-1159

9 Item(s)

per page
Axon ID Name Description From price
1590 Decitabine DNA methyltransferase inhibitor €85.00
2701 EED226 Potent, selective and orally bioavailable PRC2 inhibitor €90.00
3900 GSK-3484862 No-covalent DNMT1-selective inhibitor Inquire
3757 GSK3685032 hydrochloride Potent first-in-class DNMT1-selective inhibitor Inquire
2223 Lomeguatrib Potent, orally active inhibitor of MGMT €135.00
1691 RG 108 DNA methyltransferase inhibitor €80.00
2347 SGI 1027 dihydrochloride Inhibitor of DNMT activity in colon cancer cell lines €110.00
3587 STM2457 First-in-class, highly potent and selective catalytic METTL3 inhibitor €130.00
1254 Zebularine DNA methyltransferase inhibitor €95.00

9 Item(s)

per page
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