Methyltransferases
Over the recent years, Axon Medchem has significantly expanded its product line in the field of oncology research tools. Among them, the DNA methyltransferase and histone methyltransferase inhibitors comprise a small, yet significant selection of this set of tools. In view of the recent focus in biology on epigenetics, and DNA methylation being the best-known epigenetic marker (see also section: Axon Ligands™ for Epigenetic Research), we aim to be up front with these products to serve researchers in their objective to develop new drugs for the treatment of cancers and study the mechanisms involved in gene expression[1].
[1] Epigenetics in Cancer. M. Esteller.N Engl J Med 2008; 358, 1148-1159
Axon ID | Name | Description | From price | |
---|---|---|---|---|
1590 | Decitabine | DNA methyltransferase inhibitor | €85.00 | |
2701 | EED226 | Potent, selective and orally bioavailable PRC2 inhibitor | €90.00 | |
3900 | GSK-3484862 | No-covalent DNMT1-selective inhibitor | Inquire | |
3757 | GSK3685032 hydrochloride | Potent first-in-class DNMT1-selective inhibitor | Inquire | |
2223 | Lomeguatrib | Potent, orally active inhibitor of MGMT | €135.00 | |
1691 | RG 108 | DNA methyltransferase inhibitor | €80.00 | |
2347 | SGI 1027 dihydrochloride | Inhibitor of DNMT activity in colon cancer cell lines | €110.00 | |
3587 | STM2457 | First-in-class, highly potent and selective catalytic METTL3 inhibitor | €130.00 | |
1254 | Zebularine | DNA methyltransferase inhibitor | €95.00 |