Methyltransferases
Over the recent years, Axon Medchem has significantly expanded its product line in the field of oncology research tools. Among them, the DNA methyltransferase and histone methyltransferase inhibitors comprise a small, yet significant selection of this set of tools. In view of the recent focus in biology on epigenetics, and DNA methylation being the best-known epigenetic marker (see also section: Axon Ligands™ for Epigenetic Research), we aim to be up front with these products to serve researchers in their objective to develop new drugs for the treatment of cancers and study the mechanisms involved in gene expression[1].
[1] Epigenetics in Cancer. M. Esteller.N Engl J Med 2008; 358, 1148-1159
| Axon ID | Name | Description | From price | |
|---|---|---|---|---|
| 2863 | AMI-1 | Inhibitor of PRMT | €99.00 | |
| 2210 | C 7280948 | Sulfone inhibitor of PRMT1 | €85.00 | |
| 2709 | CMP5 | Inhibitor of PRMT5 | €95.00 | |
| 2831 | EPZ 015666 | Potent, selective and orally available inhibitor of PRMT5 | €125.00 | |
| 2710 | HLCL65 hydrochloride | Inhibitor of PRMT5 | €105.00 | |
| 3681 | MS023 dihydrochloride | Potent, cell-active, and Type I selective PRMT inhibitor | €90.00 | |
| 3692 | PF-06939999 dihydrochloride | SAM competitive PRMT5 inhibitor | Inquire | |
| 2211 | PRMT3 inhibitor 1 | Allosteric inhibitor of protein arginine methyltransferase 3 (PRMT3) | €105.00 | |
| 2625 | SGC2085 | Potent and selective CARM1 inhibitor (aka PRMT4) | €120.00 | |
| 2945 | SGC707 | First-in-class, potent, selective and cell-active allosteric inhibitor of PRMT3 | €90.00 | |