Over the recent years, Axon Medchem has significantly expanded its product line in the field of oncology research tools. Among them, the DNA methyltransferase and histone methyltransferase inhibitors comprise a small, yet significant selection of this set of tools. In view of the recent focus in biology on epigenetics, and DNA methylation being the best-known epigenetic marker (see also section: Axon Ligands™ for Epigenetic Research), we aim to be up front with these products to serve researchers in their objective to develop new drugs for the treatment of cancers and study the mechanisms involved in gene expression[1].

[1] Epigenetics in Cancer. M. Esteller.N Engl J Med 2008; 358, 1148-1159

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Axon ID Name Description From price
2863 AMI-1 Inhibitor of PRMT €99.00
2210 C 7280948 Sulfone inhibitor of PRMT1 €85.00
2709 CMP5 Inhibitor of PRMT5 €95.00
2831 EPZ 015666 Potent, selective and orally available inhibitor of PRMT5 €125.00
2710 HLCL65 hydrochloride Inhibitor of PRMT5 €105.00
3681 MS023 dihydrochloride Potent, cell-active, and Type I selective PRMT inhibitor €90.00
3692 PF-06939999 dihydrochloride SAM competitive PRMT5 inhibitor Inquire
2211 PRMT3 inhibitor 1 Allosteric inhibitor of protein arginine methyltransferase 3 (PRMT3) €105.00
2625 SGC2085 Potent and selective CARM1 inhibitor (aka PRMT4) €120.00
2945 SGC707 First-in-class, potent, selective and cell-active allosteric inhibitor of PRMT3 €90.00

10 Item(s)

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