Kinases (Tyrosine Specific Protein)

Tyrosine specific kinases form a large family of enzymes that are responsible for catalyzing the transfer of ATP to specific tyrosine residues in target proteins. In turn, the phosphorylation of tyrosine residues causes a change in the function of the protein that they are contained in. They function in a variety of processes, signal transduction pathways, and actions, and may be responsible for key events in the body[1]. Axon Ligands™ that interact with tyrosine specific enzymes that are part of the JAK/STAT signaling pathway have been categorized independently. The remainder of Axon Ligands™ that lack interactions with tyrosine kinases of this particular signaling pathway are listed here, grouped on the basis of their selectivity.


[1] Receptor tyrosine kinase signaling: a view from quantitative proteomics. J. Dengjel,I. Kratchmarova, B. Blagoev. Mol. Biosyst. 2009, 5, 1112-1121.

10 Item(s)

per page
Axon ID Name Description From price
1892 1-NM-PP1 Potent tyrosine kinase inhibitor (TKI) of multiple targets (Src, Fyn, Abl, CDK, Trk) €95.00
1456 AZD 0530 difumarate Inhibitor of SRC and ABL tyrosine kinases €70.00
2978 Brigatinib Potent, selective, and orally active anaplastic lymphoma kinase (ALK) inhibitor €80.00
2097 CGP 77675 Src Family kinase (SFK) inhibitor €65.00
3270 Lj-1-60 Fyn inhibitor targeting the Fyn/Stat3 pathway €90.00
1941 MLR 1023 Selective allosteric activator of Lyn kinase €95.00
1416 NVP-TAE684 NPM-ALK inhibitor €50.00
3284 Saracatinib Inhibitor of SRC and ABL tyrosine kinases €70.00
2778 Squarunkin A Selective UNC119–cargo interaction inhibitor €125.00
1136 SU 6656 SRC kinase inhibitor €120.00

10 Item(s)

per page
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