Diacylglycerol O-acyltransferase 1 (DGAT1; EC 188.8.131.52) catalyzes the final step of the synthesis of triglycerides (TG) and plays a critical role in dietary fat absorption in the small intestine. Therefore, it is a potential therapeutic target for treatment of obesity and related metabolic diseases. The co-enzyme Acyl-CoA is the donor substrate of the acetyl group that is transferred to the diglyceride substrates of DGAT1.
 Y. Hiramine, T. Tanabe. Characterization of acyl-coenzyme A:diacylglycerol acyltransferase (DGAT) enzyme of human small intestine. J. Physiol. Biochem. 2011, 67, 259-264.