Protein Labeling Reagents

To date, it is nearly impossible to visualize a single protein by its natural fluorescence. Therefore, to see a protein by visible light, a fluorescence probe or a green fluorescence protein (GFP) attached to the target protein is required. Over the last decade, rapid advances have been witnessed in the area and the recognition of this field was awarded with Nobel Prize of Chemistry in 2008. A fluorescent protein or a fluorescent probe can report a wealth of information about the target protein, allowing its location to be tracked, and its interactions with partners or surrounding environment to be recorded[1]. Functionalized phenylboronic acid reagents for example, may be used for palladium-catalyzed oxidative Heck reaction to protein-bound alkenes and Suzuki-Miyaura cross coupling for labeling of protein bound phenylhalides[2].


[1] W.H. Chang et al. Bio-orthogonal Protein Labeling Methods for Single Molecule FRET. J. Chin. Chem. Soc. 2010, 57, 505-513.
[2] M.E. Ourailidou et al. Aqueous oxidative Heck reaction as a protein-labeling strategy. Chembiochem. 2014, 15, 209-212.

3 Item(s)

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Axon ID Name Description From price
2256 Biotinyl-phenylboronic acid Biotinylated arylboronic acid for bio-orthogonal chemistry €95.00
2257 Dansyl-PEG-phenylboronic acid Dansylamide functionalized PEG-phenylboronic acid; Protein labeling reagent €120.00
2494 Luciferin, D- Natural substrate of firefly luciferase. Compound for bioluminescence imaging (BLI) €85.00

3 Item(s)

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