Cytogenin

Based on 20 reference(s) in Google Scholar 80 100 20

Axon N0043

CAS [132971-59-6]

MF C11H10O5
MW 222.19

Purity: >95%
Optical purity: Optically pure
Soluble in DMSO

Cytogenin

Description

Immunomodulative antitumor compound. Active as antitumor, immunomodulator, angiogenesis inhibitor, anti-inflammatory, anti-arthritic and anti-diabetic.

Source information: Streptoverticillium eurocidicum MI43-37F11

H Kumagai et al. Cytogenin a novel antitumor substance. J Antibiot (Tokyo). 1990 Nov;43(11):1505-7.

H Kumagai H, et al. Antitumor activity of cytogenin. J Antibiot (Tokyo). 1995 Feb;48(2):175-8.

Yoshioka T, et al. Production of antibiotic MI43-37F11 and production intermediate. 1992, patent JPH04112884

H Kumagai et al. Action of cytogenin on lymphoid cells and their cytokine production. J Antibiot (Tokyo). 1995 Apr;48(4):317-20.

S Hirano et al. Effects of cytogenin, a novel anti-arthritic agent, on type II collagen-induced arthritis in DBA/1J mice and adjuvant arthritis in Lewis rats. Int J Tissue React. 1994;16(4):155-62.

H Kumagai et al. Effect of cytogenin, a novel immunomodulator, on streptozotocin-induced diabetes in mice. J Antibiot (Tokyo). 2005 Mar;58(3):202-5.

T Oikawa et al. Effects of cytogenin, a novel microbial product, on embryonic and tumor cell-induced angiogenic responses in vivo. Anticancer Res. 1997 May-Jun;17(3C):1881-6.

Natural product

Angiogenesis inhibitor, immunomodulator

Chemical name

Parent CAS No.

[132971-59-6]

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N0045	NM-3	Antitumor, angiogenesis inhibitor		Inquire

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