JavaScript seems to be disabled in your browser.
You must have JavaScript enabled in your browser to utilize the functionality of this website.

Axon Medchem

All

Home
Products
- Shop By Category
- Featured Products
- Shop By Alphabet
  - A
  - B
  - C
  - D
  - E
  - F
  - G
  - H
  - I
  - J
  - K
  - L
  - M
  - N
  - O
  - P
  - Q
  - R
  - S
  - T
  - U
  - V
  - W
  - X
  - Y
  - Z
  - #
Support
- - Customer Support
  - Customer Services
Contact
- About Axon Medchem
- Contact Us

Piericidin A1 - AR 054 | Shaoguanmycin B | SN 198E

Based on 240 reference(s) in Google Scholar 8 10 240

Axon N0038

CAS [2738-64-9]

MF C25H37NO4
MW 415.57

Purity: >90%
Optical purity: Optically pure
Soluble in DMSO, EtOH and MeOH

Piericidin A1

Description

NADH:ubiquinone oxidoreductase inhibitor. Source information: Streptomyces mobaraensis

N Takahashi et al. Structure of Piercidin A.. J Am Chem Soc. 1965 May 5;87:2066-8.

JG Okun et al. Three classes of inhibitors share a common binding domain in mitochondrial complex I (NADH:ubiquinone oxidoreductase). J Biol Chem. 1999 Jan 29;274(5):2625-30.

N Ikezawa et al. Inhibition of photosystem II of spinach by the respiration inhibitors piericidin A and thenoyltrifluoroacetone. Biosci Biotechnol Biochem. 2002 Sep;66(9):1925-9.

JH Hwang et al. Etoposide-resistant HT-29 human colon carcinoma cells during glucose deprivation are sensitive to piericidin A, a GRP78 down-regulator. J Cell Physiol. 2008 Apr;215(1):243-50.

X Zhou X et al. The unique chemistry and biology of the piericidins. J Antibiot (Tokyo). 2016 Aug;69(8):582-93.

Natural product

NADH:ubiquinone oxidoreductase inhibitor

Chemical name

2-((2E,5E,7E,9R,10R,11E)-10-hydroxy-3,7,9,11-tetramethyltrideca-2,5,7,11-tetraenyl)-5,6-dimethoxy-3-methylpyridin-4-ol

Parent CAS No.

[2738-64-9]

Please wait...