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Erbstatin - MH 435A

Based on 210 reference(s) in Google Scholar 8 10 210

Axon N0021

CAS [100827-28-9]

MF C9H9NO3
MW 179.17

Purity: >90%
Optical purity: Optically pure
Soluble in DMSO and MeOH

Erbstatin

Description

Inhibitor of epidermal growth factor (EGF) receptor associated tyrosine kinase. Source information: Streptomyces sp. MH435-hF3

Umezawa K. Induction of cellular differentiation and apoptosis by signal transduction inhibitors. Adv Enzyme Regul. 1997;37:393-401.

J Markovits et al. Inhibition of DNA topoisomerases I and II and induction of apoptosis by erbstatin and tyrphostin derivatives. Biochem Pharmacol. 1994 Aug 3;48(3):549-60.

Natural product

Inhibitor of epidermal growth factor (EGF) receptor associated tyrosine kinase

Chemical name

(E)-N-(2,5-dihydroxystyryl)formamide

Parent CAS No.

[100827-28-9]

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