Cytostatin sodium salt - NSC 675266

Based on 27 reference(s) in Google Scholar 8 10 27

Axon N0018

CAS [457070-06-3]

MF C21H32NaO7P
MW 450.44

Purity: >75%
Optical purity: Optically pure
Soluble in water, DMSO and MeOH

Cytostatin sodium salt

Description

Protein Phosphatase 2A (PP2A) specific inhibitor, inhibits cancer cell adhesion to extracellular matrix.

Source information: Streptomyces sp. MJ654-NF4

Keywords: Cytostatin sodium salt | Supplier | Protein Phosphatase 2A (PP2A) specific inhibitor | NSC 675266 | NSC675266 | NSC-675266 | Antibiotic MJ 654NF4 | (+)-Cytostatin | 10664 | CAS [457070-06-3] | [156856-30-3] | Natural product

M Amemiya et al. Cytostatin, a novel inhibitor of cell adhesion to components of extracellular matrix produced by Streptomyces sp. MJ654-NF4. I. Taxonomy, fermentation, isolation and biological activities. J Antibiot (Tokyo). 1994 May;47(5):536-40.

M Kawada et al. Cytostatin, an inhibitor of cell adhesion to extracellular matrix, selectively inhibits protein phosphatase 2A. Biochim Biophys Acta. 1999 Nov 11;1452(2):209-17.

PP2A Natural product

Protein Phosphatase 2A (PP2A) specific inhibitor

Chemical name

Sodium (2S,5S,6S,7S,8Z,10Z,12E)-7-hydroxy-6-methyl-2-((2S,3S)-3-methyl-6-oxo-3,6-dihydro-2H-pyran-2-yl)tetradeca-8,10,12-trien-5-yl hydrogenphosphate

Parent CAS No.

[156856-30-3]

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Cytostatin sodium salt - NSC 675266

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Cytostatin sodium salt - NSC 675266

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