JavaScript seems to be disabled in your browser.
You must have JavaScript enabled in your browser to utilize the functionality of this website.

Axon Medchem

All

Home
Products
- Shop By Category
- Featured Products
- Shop By Alphabet
  - A
  - B
  - C
  - D
  - E
  - F
  - G
  - H
  - I
  - J
  - K
  - L
  - M
  - N
  - O
  - P
  - Q
  - R
  - S
  - T
  - U
  - V
  - W
  - X
  - Y
  - Z
  - #
Support
- - Customer Support
  - Customer Services
Contact
- About Axon Medchem
- Contact Us

COTC

Based on 8 reference(s) in Google Scholar 8 10 8

Axon N0015

CAS [57449-30-6]

MF C11H14O6
MW 242.23

Purity: >90%
Optical purity: Optically pure
Soluble in water, DMSO and MeOH

COTC

Description

Glyoxylase-I inhibitor, a strong growth inhibitor of HeLa cells and Ehrlich ascites carcinoma with low toxicity .

Source information: Streptomyces griseosporeus, MD287-CF3

Keywords: COTC | Supplier | Glyoxylase-I and HeLa cells growth inhibitor | 14675 | CAS [57449-30-6] | Axon Medchem | Axon N0015 | Natural product

T Takeuchi et al. A glyoxalase I inhibitor of a new structural type produced by Streptomyces. J Antibiot (Tokyo). 1975 Oct;28(10):737-42.

Q Zhang et al. Alkylation of nucleic acids by the antitumor agent COMC. Org Lett. 2002 May 2;4(9):1459-62.

Natural product

Glyoxylase-I inhibitor, HeLa cells growth inhibitor and Ehrlich ascites carcinoma

Chemical name

(E)-((3R,4R,5R)-3,4,5-trihydroxy-6-oxocyclohex-1-enyl)methyl but-2-enoate

Parent CAS No.

[57449-30-6]

Related Products

Axon ID	Name	Description	From price
2326	Temozolomide	DNA methylating agent; apoptosis inducer		€50.00
2327	NEO 212	DNA alkylating agent; chemotherapeutic		€110.00
3459	Dacarbazine	DNA alkylating agent; antineoplastic agent		€50.00
N0014	COMC	Inhibits the proliferation of B16 murine melanoma cells		Inquire
N0016	6-epi-COMC	Active Cytotoxin		Inquire

Please wait...