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COMC

Based on 8 reference(s) in Google Scholar 8 10 8

Axon N0014

CAS [106281-45-2]

MF C11H14O3
MW 194.23

Purity: >90%
Optical purity: Optically pure
Soluble in DMSO(Unstable in alcohols)

COMC

Description

Cytotoxic activities.

Keywords: COMC | Supplier | B16 murine melanoma cells proliferation Inhibitor | 2-Crotonyloxymethyl-2-cyclohexenone | 14701 | CAS [106281-45-2] | DNA | DNA | Inhibitor | Unclassified

Q Zhang et al. Alkylation of nucleic acids by the antitumor agent COMC. Org Lett. 2002 May 2;4(9):1459-62.

E Joseph et al. Molecular basis of the antitumor activities of 2-crotonyloxymethyl-2-cycloalkenones. J Med Chem. 2003 Jan 2;46(1):194-6.

E Joseph et al. Selective inhibition of MCF-7(piGST) breast tumors using glutathione transferase-derived 2-methylene-cycloalkenones. J Med Chem. 2005 Oct 20;48(21):6549-52.

Apoptosis inducer

Inhibits the proliferation of B16 murine melanoma cells

Chemical name

(E)-(6-oxocyclohex-1-enyl)methyl but-2-enoate

Parent CAS No.

[106281-45-2]

Related Products

Axon ID	Name	Description	From price
2326	Temozolomide	DNA methylating agent; apoptosis inducer		€50.00
2327	NEO 212	DNA alkylating agent; chemotherapeutic		€110.00
3459	Dacarbazine	DNA alkylating agent; antineoplastic agent		€50.00
N0015	COTC	Glyoxylase-I inhibitor, HeLa cells growth inhibitor and Ehrlich ascites carcinoma		Inquire
N0016	6-epi-COMC	Active Cytotoxin		Inquire

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