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Benastatin C

Based on 20 reference(s) in Google Scholar 80 100 20

Axon N0009

CAS [150151-88-5]

MF C29H28O5
MW 456.53

Purity: >90%
Optical purity: Optically pure
Soluble in DMSO and MeOH

Benastatin C

Description

Glutathione S-Transferase (GST) π Class Inhibitor, excellent stimulatory activities on the murine lymphocyte blastogenesis.

Source information: Streptomyces sp. MI384-DF12

Keywords: Benastatin C | Supplier | GST π class inhibitor | 380 | CAS [150151-88-5] | Natural product | Natural product | Natural product | Antibiotic | Apoptosis

T Aoyagi et al. Benastatins A and B, new inhibitors of glutathione S-transferase, produced by Streptomyces sp. MI384-DF12. I. Taxonomy, production, isolation, physico-chemical properties and biological activities. J Antibiot (Tokyo). 1992 Sep;45(9):1385-90.

Z Xu et al. Molecular analysis of the benastatin biosynthetic pathway and genetic engineering of altered fatty acid-polyketide hybrids. J Am Chem Soc. 2007 May 9;129(18):6022-30.

I Kakizaki et al. Induction of apoptosis and cell cycle arrest in mouse colon 26 cells by benastatin A. Jpn J Cancer Res. 2000 Nov;91(11):1161-8.

Apoptosis Cell Signaling & Oncology Apoptosis inducer Antibiotics Natural product

Glutathione S-Transferase (GST) π Class Inhibitor, activities on the murine lymphocyte blastogenesis.

Chemical name

1,7,9,11-tetrahydroxy-13,13-dimethyl-3-pentylbenzo[a]tetracen-8(13H)-one

Parent CAS No.

[150151-88-5]

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