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Benastatin B

Based on 20 reference(s) in Google Scholar 80 100 20

Axon N0008

CAS [138968-86-2]

MF C30H30O7
MW 502.56

Purity: >90%
Optical purity: Optically pure
Soluble in DMSO

Benastatin B

Description

Glutathione S-Transferase (GST) π Class Inhibitor, anti-MRSA.

Source information: Streptomyces sp. MI384-DF12

Keywords: Benastatin B | Supplier| GST π class inhibitor | 14653 | CAS [138968-86-2] | Axon Medchem | Natural product | Antibiotic | Apoptosis

T Aoyagi et al. Benastatins A and B, new inhibitors of glutathione S-transferase, produced by Streptomyces sp. MI384-DF12. I. Taxonomy, production, isolation, physico-chemical properties and biological activities. J Antibiot (Tokyo). 1992 Sep;45(9):1385-90.

Z Xu et al. Molecular analysis of the benastatin biosynthetic pathway and genetic engineering of altered fatty acid-polyketide hybrids. J Am Chem Soc. 2007 May 9;129(18):6022-30.

I Kakizaki et al. Induction of apoptosis and cell cycle arrest in mouse colon 26 cells by benastatin A. Jpn J Cancer Res. 2000 Nov;91(11):1161-8.

Apoptosis Cell Signaling & Oncology Immunology Pain & Inflammation Apoptosis inducer Antibiotics Infectious Disease Natural product

Glutathione S-Transferase (GST) π class inhibitor, anti-MRSA

Chemical name

1,7,9,11-tetrahydroxy-13,13-dimethyl-8-oxo-3-pentyl-5,6,8,13-tetrahydrobenzo[a]tetracene-2-carboxylic acid

Parent CAS No.

[138968-86-2]

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