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UNC0379 trifluoroacetate

Based on 20 reference(s) in Google Scholar 8 10 20

Axon 4380

CAS [1620401-83-3]

MF C23H35N5O2·2C2HF3O2
MW 641.60

  • Purity: 99%
  • Soluble in water, DMSO and EtOH
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UNC0379 trifluoroacetate

Description

Substrate competitive inhibitor of the H4K20 HMTase SETD8 (IC50 value 7.3 µM) with selectivity over 15 other methyltransferases including G9a and GLP. MOA studies revealed that UNC0379 is noncompetitive with the cofactor S-adenosyl-Lmethionine (SAM). The free base UNC0379 is available as Axon 2418.

KEYWORDS: UNC0379 trifluoroacetate | Supplier | SETD8 HMTase inhibitor | UNC 0379 | UNC-0379 | CAS [1620401-82-2] | CAS [1620401-83-3] | Histone | HMTase | Inhibitor | Enzymes

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Size Unit Price Stock
10 mg €125.00 In Stock
50 mg €450.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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